Evidence map›Paper›PMID 38838068›Full record

ArticleHippocampus2024

Low rate hippocampal delay period activity encodes behavioral experience.

Markos Athanasiadis, Stefano Masserini, Li Yuan, Dustin Fetterhoff, Jill K Leutgeb, Stefan Leutgeb, Christian Leibold

Abstract read
In one paragraph

Article in Hippocampus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Markos AthanasiadisFakultät für Biologie, Bernstein Center Freiburg, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.ORCID 0000-0002-5281-5207
Stefano MasseriniComputational Neurophysics Lab, Institute for Theoretical Physics, Universität Bremen, Bremen, Germany.ORCID 0009-0002-6672-0660
Li YuanNeurobiology Department, School of Biological Sciences, University of California San Diego, La Jolla, California, USA.ORCID 0000-0002-5590-0300
Dustin FetterhoffDepartment Biologie II, Ludwig-Maximilians Universität München, Martinsried, Germany.ORCID 0000-0003-3462-7832
Jill K LeutgebNeurobiology Department, School of Biological Sciences, University of California San Diego, La Jolla, California, USA.ORCID 0000-0002-2014-842X
Stefan LeutgebNeurobiology Department, School of Biological Sciences, University of California San Diego, La Jolla, California, USA.ORCID 0000-0003-3367-6536
Christian LeiboldFakultät für Biologie, Bernstein Center Freiburg, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.ORCID 0000-0002-4859-8000

Funding

Memory processing after neuron loss in the entorhinal cortex and hippocampusR01NS086947 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LEUTGEB, STEFAN · 2014 to 2024
$3.9M
Hippocampal network mechanisms for memory-guided behaviorR01MH119179 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LEUTGEB, JILL K · 2019 to 2023
$1.8M
German Research Association INST 39/963-1 FUGGGerman Research Association LE2250/12-1German Research Association LE2250/20-1NIH HHS R01MH119179NIH HHS R01 NS086947NIMH NIH HHS R01 MH119179NINDS NIH HHS R01 NS086947
6 · The paper itself

Abstract

Remembering what just happened is a crucial prerequisite to form long-term memories but also for establishing and maintaining working memory. So far there is no general agreement about cortical mechanisms that support short-term memory. Using a classifier-based decoding approach, we report that hippocampal activity during few sparsely distributed brief time intervals contains information about the previous sensory motor experience of rodents. These intervals are characterized by only a small increase of firing rate of only a few neurons. These low-rate predictive patterns are present in both working memory and non-working memory tasks, in two rodent species, rats and Mongolian gerbils, are strongly reduced for rats with medial entorhinal cortex lesions, and depend on the familiarity of the sensory-motor context.

Indexed as

Action PotentialsGerbillinaeHippocampusMemory, Short-TermAnimalsBehavior, AnimalEntorhinal CortexMaleNeuronsRatsRecognition, Psychologyadversarial attacksCA1CA3decodinghippocampusworking memory

Identifiers

PMID38838068
PMCPMC11978360

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.