Evidence map›Paper›PMID 38838014›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

The role of mitochondria in sex- and age-specific gene expression in a species without sex chromosomes.

Ning Li, Ben A Flanagan, Suzanne Edmands

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Ning LiDepartment of Biological Sciences, University of Southern California, Los Angeles, CA 90089.ORCID 0000-0002-5080-5726
Ben A FlanaganDepartment of Biological Sciences, University of Southern California, Los Angeles, CA 90089.
Suzanne EdmandsDepartment of Biological Sciences, University of Southern California, Los Angeles, CA 90089.

Funding

A new invertebrate model for the mitochondrial basis of agingR21AG055873 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI EDMANDS, SUZANNE · 2017 to 2018
$450k
HHS | NIH | National Institute on Aging (NIA) R21AG055873National Science Foundation (NSF) DEB-1656048NIA NIH HHS R21 AG055873
6 · The paper itself

Abstract

Mitochondria perform an array of functions, many of which involve interactions with gene products encoded by the nucleus. These mitochondrial functions, particularly those involving energy production, can be expected to differ between sexes and across ages. Here, we measured mitochondrial effects on sex- and age-specific gene expression in parental and reciprocal F1 hybrids between allopatric populations of

Indexed as

MitochondriaSex ChromosomesAgingAnimalsCell NucleusDNA, MitochondrialEnergy MetabolismFemaleGene Expression RegulationMaleOxidative PhosphorylationSex CharacteristicsDNA, MitochondrialhybridlongevitymitochondriaRNA-seqsex differences

Identifiers

PMID38838014
PMCPMC11181141

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.