Evidence map›Paper›PMID 38838011›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

ADH1B, the adipocyte-enriched alcohol dehydrogenase, plays an essential, cell-autonomous role in human adipogenesis.

Jérémie Gautheron, Solaf Elsayed, Valeria Pistorio, Sam Lockhart, Jamila Zammouri, Martine Auclair, Albert Koulman, Sarah R Meadows, Marie Lhomme, Maharajah Ponnaiah and 11 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Centriolar Protein POC5 Regulates Human Adipogenesis and Cellular Senescence: Insights From a Novel Metabolic Ciliopathy.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  4. Effect ofBJPsych open · 2026
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Jérémie GautheronCentre de Recherche Saint-Antoine, Sorbonne Université-Inserm, Paris 75012, France.
Solaf ElsayedMedical Genetics Department, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt.
Valeria PistorioCentre de Recherche Saint-Antoine, Sorbonne Université-Inserm, Paris 75012, France.
Sam LockhartWellcome Trust-Medical Research Council Institute of Metabolic Science, University of Cambridge, Cambridge CB2 1TN, United Kingdom.
Jamila ZammouriCentre de Recherche Saint-Antoine, Sorbonne Université-Inserm, Paris 75012, France.
Martine AuclairCentre de Recherche Saint-Antoine, Sorbonne Université-Inserm, Paris 75012, France.
Albert KoulmanWellcome Trust-Medical Research Council Institute of Metabolic Science, University of Cambridge, Cambridge CB2 1TN, United Kingdom.
Sarah R MeadowsWellcome Trust-Medical Research Council Institute of Metabolic Science, University of Cambridge, Cambridge CB2 1TN, United Kingdom.
Marie LhommeOmics Lipidomics, Foundation for Innovation in Cardiometabolism and Nutrition, Paris 75013, France.
Maharajah PonnaiahData sciences unit, Foundation for Innovation in Cardiometabolism and Nutrition, Paris 75013, France.
Redouane Si-BouazzaViral Vector and Gene Transfer Platform, Structure Federative de Recherche Necker, Université Paris Cité, Paris 75015, France.
Sylvie FabregaViral Vector and Gene Transfer Platform, Structure Federative de Recherche Necker, Université Paris Cité, Paris 75015, France.ORCID 0000-0002-4145-5488
Abdelaziz BelkadiBioinformatics Core, Weill Cornell Medicine-Qatar, Education City, Doha 24144, Qatar.
Qatar Genome ProjectQatar Genome Program, Foundation Research, Development and Innovation, Qatar Foundation, Doha 24144, Qatar.
Jean-Louis DelaunayCentre de Recherche Saint-Antoine, Sorbonne Université-Inserm, Paris 75012, France.
Tounsia Aït-SlimaneCentre de Recherche Saint-Antoine, Sorbonne Université-Inserm, Paris 75012, France.
Bruno FèveCentre de Recherche Saint-Antoine, Sorbonne Université-Inserm, Paris 75012, France.
Corinne VigourouxCentre de Recherche Saint-Antoine, Sorbonne Université-Inserm, Paris 75012, France.ORCID 0000-0002-8181-4721
Tawhida Y Abdel GhaffarYassin Abdelghaffar Center for Liver Disease and Research, Cairo 11566, Egypt.
Stephen O'Rahilly *Wellcome Trust-Medical Research Council Institute of Metabolic Science, University of Cambridge, Cambridge CB2 1TN, United Kingdom.ORCID 0000-0003-2199-4449
Isabelle Jéru *Centre de Recherche Saint-Antoine, Sorbonne Université-Inserm, Paris 75012, France.

Funding

Agence Nationale de la Recherche (ANR) ANR-21-CE18-0002-01Fondation pour la Recherche Médicale (FRM) ARF20170938613Fondation pour la Recherche Médicale (FRM) EQU201903007868Fondation pour la Recherche Médicale (FRM) EQU202003010517Mairie de Paris R18139DDSociété Francophone du Diabète (SFD) R19114DDWellcome TrustWellcome Trust (WT) 214274/z/18/z
6 · The paper itself

Abstract

Alcohol dehydrogenase 1B (ADH1B) is a primate-specific enzyme which, uniquely among the ADH class 1 family, is highly expressed both in adipose tissue and liver. Its expression in adipose tissue is reduced in obesity and increased by insulin stimulation. Interference with

Indexed as

AdipocytesAdipogenesisAlcohol DehydrogenaseAdipose TissueCell DifferentiationCRISPR-Cas SystemsHumansMutation, MissenseTretinoinADH1B protein, humanAlcohol DehydrogenaseTretinoin9-cis retinoic acidADH1Badipocyte differentiationalcohol dehydrogenase 1Bhuman adipose stem cells

Identifiers

PMID38838011
PMCPMC11181076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.