Evidence map›Paper›PMID 38837666›Full record

ReviewJournal of cellular and molecular medicine2024

Natural killer cell-related anti-tumour adoptive cell immunotherapy.

Yuwen Qi, Ying Li, Hua Wang, Anjin Wang, Xuelian Liu, Ziyan Liang, Yang Gao, Liqing Wei

Abstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Feeder-cell-free system forFrontiers in immunology · 2025
    Article
  4. Review
  5. Article
  6. Natural killer cell-related anti-tumour adoptive cell immunotherapy.Journal of cellular and molecular medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuwen QiDepartment of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Ying LiPhysical Examination Center, Renmin Hospital of Wuhan University, Wuhan, China.
Hua WangDepartment of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Anjin WangDepartment of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Xuelian LiuDepartment of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Ziyan LiangDepartment of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Yang GaoDepartment of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.ORCID 0000-0003-1785-5542
Liqing WeiWuhan Wuchang Hospital, Wuhan University of Science and Technology, Wuhan, China.ORCID 0000-0001-9882-5307

Funding

The Fundamental Research Funds for the Central Universities 2042023kf0056Zhongnan Hospital of Wuhan University Science, Technology and Innovation Seed Fund CXPY2022024
6 · The paper itself

Abstract

Chimeric antigen receptor- (CAR-)modified T cells have been successfully used to treat blood cancer. With the improved research on anti-tumour adoptive cell therapy, researchers have focused on immune cells other than T lymphocytes. Natural killer (NK) cells have received widespread attention as barriers to natural immunity. Compared to T lymphocyte-related adoptive cell therapy, the use of NK cells to treat tumours does not cause graft-versus-host disease, significantly improving immunity. Moreover, NK cells have more sources than T cells, and the related modified cells are less expensive. NK cells function through several pathways in anti-tumour mechanisms. Currently, many anti-tumour clinical trials have used NK cell-related adoptive cell therapies. In this review, we have summarized the recent progress in NK cell-related adoptive cellular immunotherapy for tumour treatment and propose the current challenges faced by CAR-NK cell therapy.

Indexed as

Immunotherapy, AdoptiveKiller Cells, NaturalNeoplasmsReceptors, Chimeric AntigenAnimalsHumansReceptors, Chimeric Antigenchallengeschimeric antigen receptor (CAR)‐T cellimmunotherapynatural killer (NK) cells

Identifiers

PMID38837666
PMCPMC11151221

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.