Evidence map›Paper›PMID 38837420›Full record

ArticleAnnals of the New York Academy of Sciences2024

Trajectories of biomedical research leading to Nobel Prize-winning discoveries.

Wendy J Burnett, E Andrew Balas, Vahe Heboyan, Kirstin R W Matthews

Abstract read
In one paragraph

Article in Annals of the New York Academy of Sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wendy J BurnettBiomedical Research Innovation Laboratory, Augusta University, Augusta, Georgia, USA.
E Andrew BalasBiomedical Research Innovation Laboratory, Augusta University, Augusta, Georgia, USA.
Vahe HeboyanSchool of Public Health, Augusta, Georgia, USA.
Kirstin R W MatthewsBaker Institute for Public Policy, Rice University, Houston, Texas, USA.

Funding

SCISIPBIO: Distinguishing practices of outstanding productivity and expansion in biomedical researchR01GM146338 · NIGMS · AUGUSTA UNIVERSITY · PI BALAS, E ANDREW · 2021 to 2023
$609k
NIGMS NIH HHS GM146338-01NIGMS NIH HHS R01 GM146338
6 · The paper itself

Abstract

Significant advancements in public health come from scientific discoveries, but more are needed to meet the ever-growing societal needs. Examining the best practices of outstanding scientists may help develop future researchers and lead to more discoveries. This study compared the comprehensive work of 49 Nobel laureates in Physiology or Medicine from 2000 to 2019 to a matched control of National Institutes of Health (NIH)-funded biomedical investigators. Our unique data set, comprising 11,737 publications, 571 US patents, and 1693 NIH research awards produced by pre-Nobel laureates, was compared to a similar data set of control researchers. Compared to control researchers, pre-Nobel laureates produce significantly more publications annually (median = 5.66; interquartile range [IQR] = 5.16); significantly fewer coauthors per publication (median = 3.32; IQR = 1.95); consistently higher Journal Impact Factor publications (median = 12.04; IQR = 6.83); and substantially more patents per researcher (median = 5; IQR = 14). Such differences arose from nearly identical cumulative NIH award budgets of pre-Nobel laureates (median $25.3 M) and control researchers. Nobel laureates are neither hyper-prolific (>72 papers per year) nor hyper-funded (>$100 M cumulative). An academic age-specific trajectory graph allows aspiring researchers to compare their productivity and collaboration patterns to those of pre-Nobel laureates.

Indexed as

Biomedical ResearchNational Institutes of Health (U.S.)Nobel PrizeHumansPatents as TopicResearch PersonnelUnited StatescollaborationsNobel laureatesresearch productivitytrajectories

Identifiers

PMID38837420
PMCPMC11187649

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.