Evidence map›Paper›PMID 38837335›Full record

ArticleJournal of the National Cancer Institute2024

Future patterns in burden and incidence of squamous cell carcinoma of the anus in the United States, 2001-2035.

Ashvita Garg, Haluk Damgacioglu, Keith Sigel, Alan G Nyitray, Gary M Clifford, Thomas Curran, Gweneth Lazenby, Eric G Meissner, Katherine Sterba, Kalyani Sonawane and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the National Cancer Institute, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ashvita GargDepartment of Public Health Sciences, College of Medicine, Medical University of South Carolina, Charleston, SC, USA.ORCID 0000-0003-4930-1712
Haluk DamgaciogluDepartment of Public Health Sciences, College of Medicine, Medical University of South Carolina, Charleston, SC, USA.ORCID 0000-0003-4361-4515
Keith SigelDivision of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-4051-4861
Alan G NyitrayClinical Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA.ORCID 0000-0003-2020-9904
Gary M CliffordEarly Detection, Prevention and Infections Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
Thomas CurranDivision of Colon and Rectal Surgery, Department of Surgery, Medical University of South Carolina, SC, USA.ORCID 0000-0002-9309-4696
Gweneth LazenbyDepartment of Obstetrics and Gynecology, Medical University of South Carolina, Charleston, SC, USA.
Eric G MeissnerDivision of Infectious Diseases, Medical University of South Carolina, Charleston, SC, USA.ORCID 0000-0002-6882-8870
Katherine SterbaDepartment of Public Health Sciences, College of Medicine, Medical University of South Carolina, Charleston, SC, USA.
Kalyani SonawaneDepartment of Public Health Sciences, College of Medicine, Medical University of South Carolina, Charleston, SC, USA.ORCID 0000-0001-5501-3034
Ashish A DeshmukhDepartment of Public Health Sciences, College of Medicine, Medical University of South Carolina, Charleston, SC, USA.

Funding

The effectiveness of screening women with lower genital tract neoplasia or cancers for anal cancer precursorsR01CA256660 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CHIAO, ELIZABETH Y., DESHMUKH, ASHISH A. · 2021 to 2025
$4.3M
Optimizing Age-based Anal Cancer Screening Among People Living with HIV using Decision Analytic ModelingR01CA232888 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI DESHMUKH, ASHISH A. · 2019 to 2022
$2.0M
Harnessing Big Data to Identify Geographic Clusters of Low-income children with Poor HPV Vaccination RatesK01MD016440 · NIMHD · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SONAWANE, KALYANI · 2021 to 2024
$464k
NCI NIH HHS R01 CA232888NCI NIH HHS R01 CA256660NIH HHS R01CA232888NIMHD NIH HHS K01 MD016440NIMHD NIH HHS K01MD016440World Health Organization 001
6 · The paper itself

Abstract

Squamous cell carcinoma of the anus (SCCA) incidence has been rising in the United States, particularly among older adults (≥65 years). We estimated the impact of this rise on future burden (through 2035) using age-period-cohort modeling. The SCCA burden (cases/year) is expected to rise, reaching approximately 2700 among men and approximately 7000 among women in 2031-2035 (burden during 2016-2020 among men and women was approximately 2150 and approximately 4600), with most cases 65 years of age or older (61% in men and 70% in women in 2031-2035; from 40% and 46% in 2016-2020). SCCA incidence (per 100 000) is projected to rise among older men aged 65-74, 75-84, and 85 years or older (5.0, 4.9, and 4.3 in 2031-2035 vs 3.7, 3.8, and 3.4 in 2016-2020, respectively) and women (11.2, 12.6, and 8.0 in 2031-2035 vs 8.2, 6.8, and 5.2 in 2016-2020, respectively). The projected rise in SCCA burden among older adults is troubling and highlights the importance of improving early detection and clinical care.

Indexed as

Anus NeoplasmsCarcinoma, Squamous CellAdultAgedAged, 80 and overCost of IllnessFemaleHumansIncidenceMaleMiddle AgedSEER ProgramUnited States

Identifiers

PMID38837335
PMCPMC11378306

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.