Evidence map›Paper›PMID 38837232›Full record

ArticleThe Laryngoscope2024

Quality of Life Outcomes for Parotid Malignancies.

Anthony Tang, Jinhong Li, Nicole Scheff, Jonas T Johnson, Kevin J Contrera, Marci L Nilsen

Abstract read
In one paragraph

Article in The Laryngoscope, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Contemporary Management of Malignancies of the Parotid Gland: A State-of-the-Art Review.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Review
  2. Review
  3. Quality of life, function, and symptom trajectory patterns following salivary gland cancer treatment: a 5-year prospective cohort study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anthony TangUniversity of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, U.S.A.ORCID 0009-0004-7381-9022
Jinhong LiDepartment of Biostatistics, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, U.S.A.
Nicole ScheffDepartment of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A.
Jonas T JohnsonDepartment of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A.ORCID 0000-0002-2376-4594
Kevin J ContreraDepartment of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A.ORCID 0000-0002-2570-1706
Marci L NilsenDepartment of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A.

Funding

Radiation-Induced Fibrosis and Co-occurring Adverse Treatment-Related Effects in Head and Neck Cancer SurvivorsR37CA279210 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MARCI LEE NILSEN · 2023 to 2026
$2.5M
Interaction Behaviors Effect on Nursing Care Quality of Older Adults in the ICUF31NR012856 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NILSEN, MARCI LEE · 2011 to 2012
$55k
NCI NIH HHS R37 CA279210NIH HHSNINR NIH HHS F31 NR012856The Gordon and Betty Moore Foundation
6 · The paper itself

Abstract

backgroundThis study describes patient-reported outcome measures (PROMs) and associated factors in patients who underwent surgery for malignant parotid tumors (MPT).

methodsThis is a retrospective study of all surgically treated MPT patients in a multidisciplinary head and neck cancer (HNC) survivorship clinic (2017-2023). PROMs included University of Washington Quality of Life Questionnaire (UW-QOL), Eating Assessment Tool (EAT-10), Patient Health Questionnaire (PHQ-8), Generalized Anxiety Disorder (GAD-7), Neck Disability Index (NDI), and Insomnia Severity Index. Multivariable regression analysis was used to investigate clinical predictors associated with PROMs.

resultsIn 62 MPT patients, the prevalence of clinically relevant dysphagia symptoms (EAT-10), elevated symptoms of depression (PHQ-8), moderate/severe symptoms of anxiety (GAD-7), moderate/severe neck pain with activities of daily living (NDI), and moderate/severe symptoms of insomnia at last follow-up was 32.3%, 15.5%, 7.1%, 17.7%, and 7.2%, respectively. Nonparametric one-sided test revealed that patients treated with adjuvant CRT had significantly worse physical QOL, social-emotional QOL, and swallowing scores than patients treated with surgery alone (p = 0.01, p = 0.02, p = 0.03, respectively); that patients treated with surgery and adjuvant RT had significantly worse physical QOL and social-emotional QOL than patients treated with surgery alone (p < 0.01, p = 0.01, respectively) and that patients treated with surgery and adjuvant CRT had significantly worse swallowing and neck pain than patients treated with surgery and adjuvant RT (p = 0.03, p = 0.05, respectively).

conclusionsIn patients with surgically treated MPT, adjuvant CRT and RT were associated with worse PROMs. LEVEL OF EVIDENCE: 4 Laryngoscope, 134:4549-4556, 2024.

Indexed as

Parotid NeoplasmsPatient Reported Outcome MeasuresQuality of LifeActivities of Daily LivingAdultAgedAnxietyChemoradiotherapy, AdjuvantDeglutition DisordersDepressionFemaleHumansMaleMiddle AgedRetrospective StudiesSleep Initiation and Maintenance Disorderscombined modality therapyparotid neoplasmspatient reported outcome measuresquality of lifesurvivorship

Identifiers

PMID38837232
PMCPMC11466688

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.