Evidence map›Paper›PMID 38836959›Full record

ArticleLasers in medical science2024

Swept-source optical coherence tomography and swept-source optical coherence tomography angiography findings in circumscribed choroidal hemangioma before and after transpupillary thermotherapy.

Ibadulla Mirzayev, Ahmet Kaan Gündüz, Ahmet Ergin

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Article in Lasers in medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Ibadulla MirzayevDepartment of Ophthalmology, Ankara University Faculty of Medicine, Ankara, Turkey.ORCID http://orcid.org/0000-0002-0161-8078
Ahmet Kaan GündüzDepartment of Ophthalmology, Ankara University Faculty of Medicine, Ankara, Turkey. drkaangunduz@gmail.com.ORCID http://orcid.org/0000-0001-5945-5657
Ahmet ErginDepartment of Ophthalmology, Balıkesir University Faculty of Medicine, Balıkesir, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the swept-source optical coherence tomography (SS-OCT) and SS-OCT angiography (SS-OCTA) findings in circumscribed choroidal hemangioma (CCH) before and after treatment with transpupillary thermotherapy (TTT).

methodsThe clinical records of 21 eyes having CCH imaged with SS-OCT/SS-OCTA between September 2018 and December 2022 were evaluated.

resultsSS-OCT examination in CCH showed dome-shaped appearance (100%), choroidal shadowing (100%), expansion of choroidal structures (100%), subretinal fluid (66.7%), intraretinal edema/schisis (33.3%), retinal pigment epithelium (RPE) atrophy (19.0%), hyperreflective dots (19.0%), and epiretinal membrane (4.8%). Internal arborizing tumor vessels showing hyperreflectivity were observed in the choriocapillaris slab on SS-OCTA in all eyes. In the deep capillary plexus (DCP), flow void changes were seen in 7 eyes with intraretinal schisis/cystoid macular edema. Four CCHs > 2 mm in thickness showed outer retinal involvement due to unmasking of flow in intratumoral vessels related to RPE atrophy. Following TTT/indocyanine green-enhanced TTT (ICG-TTT) of CCH, SS-OCT findings included total/partial resolution of subretinal fluid (57.1%), complete/partial regression of the tumor (52.4%), and RPE atrophy (33.3%). After treatment; loss of choriocapillaris, decrease in tumor vascularity together with increase in the fibrous component and flow void areas were detected on SS-OCTA.

conclusionsSS-OCT/SS-OCTA are useful non-invasive tools for imaging the structural/vascular changes in CCHs managed with TTT or ICG-TTT. On SS-OCTA, hyporeflective spaces localizing to edema/schisis in the DCP and arborizing tumor vessels within a hyporeflective stromal background in the choriocapillaris slab were observed. After TTT/ICG-TTT, a decrease in tumor vessels and an increase in the fibrous component and flow-void areas inside the CCH were detected on SS-OCTA.

Indexed as

Choroid NeoplasmsHemangiomaHyperthermia, InducedTomography, Optical CoherenceAdultAgedChoroidFemaleFluorescein AngiographyHumansMaleMiddle AgedRetrospective StudiesCircumscribed choroidal hemangiomaIndocyanine green-enhanced transpupillary thermotherapyInternal tumor vesselsSwept-source optical coherence tomography angiographyTranspupillary thermotherapy

Identifiers

PMID38836959
PMCPMC11153281

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