Evidence map›Paper›PMID 38836601›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2024

Epidemiology of Respiratory Syncytial Virus in Adults and Children With Medically Attended Acute Respiratory Illness Over Three Seasons.

Katherine M Begley, Aleda M Leis, Joshua G Petrie, Rachel Truscon, Emileigh Johnson, Lois E Lamerato, Melissa Wei, Arnold S Monto, Emily T Martin

Abstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Multimorbidity Profiles and Severe In-Hospital Outcomes in Adults With Respiratory Syncytial Virus.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Katherine M BegleyDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
Aleda M LeisDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
Joshua G PetrieDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
Rachel TrusconDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
Emileigh JohnsonDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
Lois E LameratoDepartment of Public Health Sciences, Henry Ford Health, Detroit, Michigan, USA.
Melissa WeiDepartment of Medicine, University of California Los Angeles, Los Angeles, California, USA.
Arnold S MontoDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
Emily T MartinDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.ORCID 0000-0002-5771-8895

Funding

Michigan Institute for Clinical and Health Research (MICHR)UM1TR004404 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Julie C Lumeng · 2023 to 2026
$39.8M
CTSA K12 Program at the University of MichiganK12TR004374 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VICKI L ELLINGROD, Leah Elizabeth Robinson · 2023 to 2026
$6.5M
NCATS NIH HHS K12 TR004374NCATS NIH HHS UM1 TR004404
6 · The paper itself

Abstract

backgroundData on the true prevalence of respiratory syncytial virus (RSV) among medically attended acute respiratory illnesses (MAARI) has been limited by the lack of regular clinical testing of mild to moderate illnesses. Here we present a prospective evaluation of the epidemiology of RSV-associated MAARI across age groups and multimorbidity status over 3 seasons, which is informative in light of the recommendations for shared decision making for vaccination in older adults.

methodsAmbulatory patients ≥6 months of age meeting a common MAARI case definition were prospectively enrolled in the Michigan Ford Influenza Vaccine Effectiveness (MFIVE) study, a subsite of the US Influenza Vaccine Effectiveness Network. All participants were tested by nasal-throat swab for RSV and influenza, including subtype, independently from clinician-directed testing. Participant illness characteristics and calculated multimorbidity-weighted index (MWI) were collected by in-person survey and electronic medical record review.

resultsOver 3 surveillance seasons (fall 2017 to spring 2020), 9.9% (n = 441) of 4442 participants had RSV detected. RSV-associated MAARI was more prevalent than influenza for participants 6 months to 4 years of age. Adults with RSV-MAARI had higher median MWI scores overall compared to influenza-MAARI and controls with neither virus (1.62, 0.40, and 0.64, respectively).

conclusionsRSV is a significant, underrecognized cause of MAARI in both children and adults presenting for ambulatory care. Multimorbidity is an important contributor to RSV-associated MAARI in outpatient adults, providing information to support shared clinical decision making for vaccination.

Indexed as

Respiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsRespiratory Tract InfectionsSeasonsAcute DiseaseAdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleHumansInfantInfluenza, HumanInfluenza VaccinesInfluenza Vaccinesadultchildmedically-attended acute respiratory illnessmultimorbidityrespiratory syncytial virus

Identifiers

PMID38836601
PMCPMC12187053

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.