Evidence map›Paper›PMID 38836382›Full record

ArticleHuman vaccines & immunotherapeutics2024

Patients with advanced cancer were treated with immune checkpoint inhibitors and injected with COVID-19 vaccine to improve their prognosis without increasing pancreatic related adverse events.

Min Li, Lingling Liao, Wei Huang, Hui Feng, Wanqing Wang, Nana Huang, Zhiyan Zhao, Yu Shi, Jinglu Ye, Kangsheng Gu

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Min LiDepartment of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Lingling LiaoDepartment of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Wei HuangDepartment of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Hui FengDepartment of Gastroenterology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Wanqing WangDepartment of Medical Imaging, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Nana HuangDepartment of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Zhiyan ZhaoDepartment of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Yu ShiDepartment of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Jinglu YeDepartment of Endocrinology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Kangsheng GuDepartment of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate immune checkpoint inhibitors (ICIs) induced pancreatic injury (ICIPI), the prognostic effect of COVID-19 vaccine on cancer patients, and whether COVID-19 vaccine increases the incidence of ICIPI. We conducted a retrospective study of 256 stage IV cancer patients treated with ICIs at The First Affiliated Hospital of Anhui Medical University from January 2020 to November 2022. Data collected included pancreatic enzyme levels, treatment outcomes, and vaccination status. Statistical significance was determined using the χ2 test and Kaplan-Meier method (

Indexed as

COVID-19COVID-19 VaccinesImmune Checkpoint InhibitorsNeoplasmsAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedPancreasPrognosisRetrospective StudiesTreatment OutcomeCOVID-19 VaccinesImmune Checkpoint InhibitorsImmune checkpoint inhibitors (ICIs)immune-related pancreatic toxicitypancreatic enzymes; COVID-19 vaccine

Identifiers

PMID38836382
PMCPMC11155700

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.