Evidence map›Paper›PMID 38835740›Full record

ArticleMedizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V2023

Liquid biopsy-based early tumor and minimal residual disease detection

Lena Bohaumilitzky, Johannes Gebert, Magnus von Knebel Doeberitz, Matthias Kloor, Aysel Ahadova

Abstract read
In one paragraph

Article in Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Liquid Biopsy: The Challenges of a Revolutionary Approach in Oncology.International journal of molecular sciences · 2025
    Review
  4. Liquid Biopsy: minimal-invasive analysis of somatic alterations.Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lena BohaumilitzkyInstitute of Pathology University Hospital Heidelberg Heidelberg Germany.ORCID https://orcid.org/0009-0005-7088-802X
Johannes GebertInstitute of Pathology University Hospital Heidelberg Heidelberg Germany.ORCID https://orcid.org/0000-0002-0606-7818
Magnus von Knebel DoeberitzInstitute of Pathology University Hospital Heidelberg Heidelberg Germany.
Matthias KloorInstitute of Pathology University Hospital Heidelberg Heidelberg Germany.
Aysel AhadovaInstitute of Pathology University Hospital Heidelberg Heidelberg Germany.ORCID https://orcid.org/0000-0001-9890-0450

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic predisposition is one of the major measurable cancer risk factors. Affected patients have an enhanced risk for cancer and require life-long surveillance. However, current screening measures are mostly invasive and only available for certain tumor types. Particularly in hereditary cancer syndromes, liquid biopsy, in addition to monitoring therapy response and assessing minimal residual disease, holds great potential for surveillance at the precancerous stage and potentially even diagnostics. Exploring these options and future clinical translation could help reduce cancer risk and mortality in high-risk individuals and enhance patients' adherence to tailored surveillance protocols.

Indexed as

cancer predisposition syndromesclinical managementearly cancer detectionLiquid biopsyLynch syndrome

Identifiers

PMID38835740
PMCPMC11006388

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.