Evidence map›Paper›PMID 38835660›Full record

ReviewFrontiers in pharmacology2024

Effects of cell-free DNA on kidney disease and intervention strategies.

Mingying Zhang, Yubin Cai, Xiaoze Zhong, Weijun Liu, Yuan Lin, Zhanyi Qiu, Ruihuang Liang, Huibo Wei, Kefei Wu, Qinghua Liu

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mingying Zhang *Department of Nephrology, Jieyang People's Hospital, Jieyang, China.
Yubin Cai *Department of Nephrology, Jieyang People's Hospital, Jieyang, China.
Xiaoze Zhong *Department of Nephrology, Jieyang People's Hospital, Jieyang, China.
Weijun LiuDepartment of Nephrology, Jieyang People's Hospital, Jieyang, China.
Yuan LinDepartment of Nephrology, Jieyang People's Hospital, Jieyang, China.
Zhanyi QiuDepartment of Nephrology, Jieyang People's Hospital, Jieyang, China.
Ruihuang LiangDepartment of Nephrology, Jieyang People's Hospital, Jieyang, China.
Huibo WeiDepartment of Nephrology, Jieyang People's Hospital, Jieyang, China.
Kefei WuDepartment of Nephrology, Jieyang People's Hospital, Jieyang, China.
Qinghua LiuDepartment of Nephrology, Jieyang People's Hospital, Jieyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kidney disease has become a global public health problem. Patients with end-stage kidney disease must rely on dialysis or undergo renal transplantation, placing heavy burdens on their families and society. Therefore, it is important to develop new therapeutic targets and intervention strategies during early stages of chronic kidney disease. The widespread application of liquid biopsy has led to an increasing number of studies concerning the roles of cell-free DNA (cfDNA) in kidney disease. In this review, we summarize relevant studies concerning the roles of cfDNA in kidney disease and describe various strategies for targeted removal of cfDNA, with the goal of establishing novel therapeutic approaches for kidney disease.

Indexed as

acute kidney injurycell-free DNAchronic kidney diseasenanomaterialneutrophil extracellular traps

Identifiers

PMID38835660
PMCPMC11148383

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.