Evidence map›Paper›PMID 38835616›Full record

ArticleFrontiers in public health2024

Fine particulate matter-sudden death association modified by ventricular hypertrophy and inflammation: a case-crossover study.

Kristen M Rappazzo, Nicole M Egerstrom, Jianyong Wu, Alia B Capone, Golsa Joodi, Susan Keen, Wayne E Cascio, Ross J Simpson

Abstract read
In one paragraph

Article in Frontiers in public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kristen M RappazzoU.S. Environmental Protection Agency, Office of Research and Development, Center for Public Health and Environmental Assessment, Research Triangle Park, NC, United States.
Nicole M EgerstromGillings Global School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Jianyong WuDivision of Environmental Health Sciences, College of Public Health, The Ohio State University, Columbus, OH, United States.
Alia B CaponeDivision of Cardiology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Golsa JoodiDivision of Cardiology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Susan KeenDivision of Cardiology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Wayne E CascioU.S. Environmental Protection Agency, Office of Research and Development, Center for Public Health and Environmental Assessment, Research Triangle Park, NC, United States.
Ross J SimpsonDivision of Cardiology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.

Funding

North Carolina Translational and Clinical Sciences Institute (NC TraCS)UM1TR004406 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NICHOLAS J SHAHEEN · 2023 to 2026
$37.5M
NCATS NIH HHS UM1 TR004406
6 · The paper itself

Abstract

Background: Sudden death accounts for approximately 10% of deaths among working-age adults and is associated with poor air quality. Objectives: To identify high-risk groups and potential modifiers and mediators of risk, we explored previously established associations between fine particulate matter (PM Methods: Sudden death victims in Wake County, NC, from 1 March 2013 to 28 February 2015 were identified by screening Emergency Medical Systems reports and adjudicated ( Results: Individuals having LVH or an NLR above 2.5 had PM Conclusion: LVH and inflammation may be the final step in the causal pathway whereby poor air quality and traditional risk factors trigger arrhythmia or myocardial ischemia and sudden death. The combination of statistical evidence with clinical knowledge can inform medical providers of underlying risks for their patients generally, while our findings here may help guide interventions to mitigate the incidence of sudden death.

Indexed as

Cross-Over StudiesHypertrophy, Left VentricularInflammationParticulate MatterAdultAgedAir PollutantsAir PollutionDeath, SuddenEnvironmental ExposureFemaleHumansMaleMiddle AgedRisk FactorsAir PollutantsParticulate Matterarrhythmia riskgreenspaceinflammationleft ventricular hypertrophymodificationparticulate mattersudden death

Identifiers

PMID38835616
PMCPMC11148389

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.