Evidence map›Paper›PMID 38835512›Full record

ArticleClinical kidney journal2024

Congestion as a crucial factor determining albuminuria in patients with cardiorenal disease.

Pau Llàcer, Marta Cobo Marcos, Rafael de la Espriella, Jara Gayán Ordás, Isabel Zegri, Aleix Fort, Adriana Rodríguez Chavarri, Ana Méndez, Zorba Blázquez, Pedro Caravaca Pérez and 13 more

Abstract read
In one paragraph

Article in Clinical kidney journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Pau LlàcerInternal Medicine Department, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain.ORCID https://orcid.org/0000-0002-0988-0599
Marta Cobo MarcosDepartment of Cardiology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
Rafael de la EspriellaDepartment of Cardiology, Hospital Clínico Universitario de Valencia, Valencia, Spain.ORCID https://orcid.org/0000-0002-8720-3999
Jara Gayán OrdásDepartment of Cardiology, Hospital Universitario Arnau de Vilanova, Institut de Recerca Biomèdica de Lleida, Lleida, Spain.
Isabel ZegriDepartment of Cardiology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Aleix FortDepartment of Cardiology, Hospital Universitari Dr Josep Trueta, Girona, Spain.
Adriana Rodríguez ChavarriDepartment of Cardiology, Hospital Universitario La Paz, Madrid, Spain.
Ana MéndezDepartment of Cardiology, Hospital Universitario Vall d'Hebron, Barcelona, Spain.
Zorba BlázquezDepartment of Cardiology, Hospital Universtiario Gregorio Marañón, Madrid, Spain.
Pedro Caravaca PérezDepartment of Cardiology, Hospital Universitario Doce de Octubre, Madrid, Spain.
Jorge Rubio GraciaDepartment of Internal Medicine, Hospital Universitario Lozano Blesa, University of Zaragoza, Zaragoza, Spain.
Cristina FernándezInternal Medicine Department, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain.
Alejandro Recio-MayoralDepartment of Cardiology, Hospital Universitario Virgen Macarena, Sevilla, Spain.
Antonia PomaresDepartment of Cardiology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Jose Manuel García PinillaDepartment of Cardiology, Hospital Universitario Virgen de la Victoria, Málaga, Spain.
Jorge Vazquez López-IborDepartment of Cardiology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
Almudena CastroDepartment of Cardiology, Hospital Universitario La Paz, Madrid, Spain.
Maria Jose SolerDepartment of Nephrology, Hospital Universitario Vall d´Hebron, Barcelona, Spain.
Jose Luis GórrizDepartment of Nephrology, Hospital Clínico Universitario Valencia, University of Valencia, Valencia, Spain.ORCID https://orcid.org/0000-0002-1134-9051
Ramón Bascompte ClaretDepartment of Cardiology, Hospital Universitario Arnau de Vilanova, Institut de Recerca Biomèdica de Lleida, Lleida, Spain.
Paula FluviàDepartment of Cardiology, Hospital Universitari Dr Josep Trueta, Girona, Spain.
Luis ManzanoInternal Medicine Department, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain.
Julio NúñezCentro de Investigación Biomédica en Red en Enfermedades Cardiovasculares, Madrid, Spain.ORCID https://orcid.org/0000-0003-1672-7119

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Albuminuria could potentially emerge as a novel marker of congestion in acute heart failure. However, the current evidence linking albuminuria and congestion in patients with congestive heart failure (CHF) remains somewhat scarce. This study aimed to evaluate the prevalence of albuminuria in a cohort of patients with CHF, identify the independent factors associated with albuminuria and analyse the correlation with different congestion parameters. Methods: This is a subanalysis of the Spanish Cardiorenal Registry, in which we enrolled 864 outpatients with heart failure and a value of urinary albumin:creatinine ratio (UACR) at the first visit. Results: The median age was 74 years, 549 (63.5%) were male and 438 (50.7%) had a reduced left ventricular ejection fraction. A total of 350 patients (40.5%) had albuminuria. Among these patients, 386 (33.1%) had a UACR of 30-300 mg/g and 64 (7.4%) had a UACR >300 mg/g. In order of importance, the independent variables associated with higher UACR were estimated glomerular filtration rate determined by the Chronic Kidney Disease Epidemiology Collaboration equation ( Conclusions: In patients with chronic stable heart failure, the prevalence of albuminuria is high. The risk factors of albuminuria in this population are chronic kidney disease and hypertension. Congestion parameters are also associated with increased albuminuria.

Indexed as

albuminuriacardiorenal diseasecongestioncongestive heart failurepredictors

Identifiers

PMID38835512
PMCPMC11145452

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.