Evidence map›Paper›PMID 38834944›Full record

ArticleBMC geriatrics2024

A novel score for predicting falls in community-dwelling older people: a derivation and validation study.

Ming Zhou, Gongzi Zhang, Na Wang, Tianshu Zhao, Yangxiaoxue Liu, Yuhan Geng, Jiali Zhang, Ning Wang, Nan Peng, Liping Huang

Abstract readValidation Study
In one paragraph

Article in BMC geriatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ming Zhou *Department of Rehabilitation Medicine, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Gongzi Zhang *Department of Rehabilitation Medicine, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Na WangDepartment of Rehabilitation Medicine, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Tianshu ZhaoDepartment of Rehabilitation Medicine, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Yangxiaoxue LiuDepartment of Rehabilitation Medicine, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Yuhan GengDepartment of Rehabilitation Medicine, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Jiali ZhangDepartment of Rehabilitation Medicine, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Ning WangDepartment of Rehabilitation Medicine, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Nan PengDepartment of Rehabilitation Medicine, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, China. pengnan301@163.com.
Liping HuangDepartment of Rehabilitation Medicine, The First Medical Center of Chinese PLA General Hospital, Beijing, China. ping-online@163.com.

Funding

National Key Research and Development Program of China 2022YFB4703200
6 · The paper itself

Abstract

backgroundEarly detection of patients at risk of falling is crucial. This study was designed to develop and internally validate a novel risk score to classify patients at risk of falls.

methodsA total of 334 older people from a fall clinic in a medical center were selected. Least absolute shrinkage and selection operator (LASSO) regression was used to minimize the potential concatenation of variables measured from the same patient and the overfitting of variables. A logistic regression model for 1-year fall prediction was developed for the entire dataset using newly identified relevant variables. Model performance was evaluated using the bootstrap method, which included measures of overall predictive performance, discrimination, and calibration. To streamline the assessment process, a scoring system for predicting 1-year fall risk was created.

resultsWe developed a new model for predicting 1-year falls, which included the FRQ-Q1, FRQ-Q3, and single-leg standing time (left foot). After internal validation, the model showed good discrimination (C statistic, 0.803 [95% CI 0.749-0.857]) and overall accuracy (Brier score, 0.146). Compared to another model that used the total FRQ score instead, the new model showed better continuous net reclassification improvement (NRI) [0.468 (0.314-0.622), P < 0.01], categorical NRI [0.507 (0.291-0.724), P < 0.01; cutoff: 0.200-0.800], and integrated discrimination [0.205 (0.147-0.262), P < 0.01]. The variables in the new model were subsequently incorporated into a risk score. The discriminatory ability of the scoring system was similar (C statistic, 0.809; 95% CI, 0.756-0.861; optimism-corrected C statistic, 0.808) to that of the logistic regression model at internal bootstrap validation.

conclusionsThis study resulted in the development and internal verification of a scoring system to classify 334 patients at risk for falls. The newly developed score demonstrated greater accuracy in predicting falls in elderly people than did the Timed Up and Go test and the 30-Second Chair Sit-Stand test. Additionally, the scale demonstrated superior clinical validity for identifying fall risk.

Indexed as

Accidental FallsIndependent LivingAgedAged, 80 and overFemaleGeriatric AssessmentHumansMalePredictive Value of TestsRisk AssessmentRisk FactorsAccidental fallsFall predictionOlder adultsRisk assessment

Identifiers

PMID38834944
PMCPMC11151514

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.