Evidence map›Paper›PMID 38834899›Full record

ArticleIrish journal of medical science2024

Relationship between aging and excess body fat with markers of inflammation, skeletal muscle mass and strength in Mexican community-dwelling people.

Víctor Manuel Mendoza-Núñez, Jimena Valeria Aguilar-Curiel, Lilia Castillo-Martínez, Wendy Daniella Rodríguez-García, Nayeli Vaquero-Barbosa, Juana Rosado-Pérez, Taide Laurita Arista-Ugalde

Abstract read
In one paragraph

Article in Irish journal of medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Víctor Manuel Mendoza-NúñezResearch Unit On Gerontology, FES Zaragoza, National Autonomous University of Mexico, Guelatao # 66, Alcaldía Iztapalapa, 09230, Mexico City, Mexico. mendovic@unam.mx.ORCID http://orcid.org/0000-0002-9137-3405
Jimena Valeria Aguilar-CurielResearch Unit On Gerontology, FES Zaragoza, National Autonomous University of Mexico, Guelatao # 66, Alcaldía Iztapalapa, 09230, Mexico City, Mexico.
Lilia Castillo-MartínezClinical Nutrition Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Wendy Daniella Rodríguez-GarcíaNutrition Career, FES Zaragoza, National Autonomous University of Mexico, 09230, Mexico City, Mexico.
Nayeli Vaquero-BarbosaResearch Unit On Gerontology, FES Zaragoza, National Autonomous University of Mexico, Guelatao # 66, Alcaldía Iztapalapa, 09230, Mexico City, Mexico.
Juana Rosado-PérezResearch Unit On Gerontology, FES Zaragoza, National Autonomous University of Mexico, Guelatao # 66, Alcaldía Iztapalapa, 09230, Mexico City, Mexico.
Taide Laurita Arista-UgaldeResearch Unit On Gerontology, FES Zaragoza, National Autonomous University of Mexico, Guelatao # 66, Alcaldía Iztapalapa, 09230, Mexico City, Mexico.

Funding

Directorate-General for Employment, Social Affairs and Inclusion PAPIIT IN306121
6 · The paper itself

Abstract

introductionAging is accompanied by changes in body composition, such as an increase in fat mass (FM), a decrease in skeletal muscle mass index (SMMI) and muscle strength, combined with a chronic inflammatory process (CI).

objectiveDetermine the relationship between age and excess body fat with markers of chronic inflammation, skeletal muscle mass and strength.

methodsA cross-sectional alitical study was carried out in a convenience sample of adults 45 to 59 years old (n = 100) and older adults 60 to 74 years old (n = 133). All participants had their body composition measured with an impedance meter. They were subsequently divided into two groups: (i) with excess fat (WEF), (ii) without excess fat (NEF), in order to relate excess fat and age with inflammation, muscle mass and strength.

resultsNEF adults and older adults had similar values of SMMI (9.1 ± 1.5 vs. 8.8 ± 1.3, p > 0.05) and strength (28 ± 8 vs. 27 ± 8.6, p > 0.05). Likewise, WEF adults showed significantly lower values than NEF adults in the SMMI (7.9 ± 0.8 vs. 9.1 ± 1.5, p < 0.05) and strength (28 ± 8 vs. 22 ± 5, p < 0.001). Also, WEF older adults presented significantly lower values in the SMMI (15.9 ± 1.8 vs. 22.8 ± 5.1, p < 0.05) and strength (17.9 ± 4.8 vs. 27 ± 8.6, p < 0.001).

conclusionsOur findings suggest that excess fat mass is a risk factor that has a significantly greater influence than aging per se on the index of skeletal muscle mass and strength.

Indexed as

Adipose TissueAgingInflammationMuscle, SkeletalMuscle StrengthAgedBiomarkersBody CompositionCross-Sectional StudiesFemaleHumansIndependent LivingMaleMexicoMiddle AgedBiomarkersAgingChronic inflammationMuscle massObesitySarcopeniaStrength

Identifiers

PMID38834899
PMCPMC11450110

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.