Evidence map›Paper›PMID 38834610›Full record

ArticleScientific reports2024

A deep dive into burn-mediated ARDS severity assessment: a retrospective study on hematological markers.

Jeongsoo Park, Dohern Kym, Jun Hur, Jaechul Yoon, Myongjin Kim, Yong Suk Cho, Wook Chun, Dogeon Yoon

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jeongsoo ParkDepartment of Surgery and Critical Care, Burn Center, Hangang Sacred Heart Hospital, Hallym University Medical Center, College of Medicine, Hallym University, 12, Beodeunaru-ro 7-gil, Yeongdeungpo-gu, Seoul, 07247, Korea.
Dohern Kym *Department of Surgery and Critical Care, Burn Center, Hangang Sacred Heart Hospital, Hallym University Medical Center, College of Medicine, Hallym University, 12, Beodeunaru-ro 7-gil, Yeongdeungpo-gu, Seoul, 07247, Korea. dohern@hallym.or.kr.
Jun Hur *Department of Surgery and Critical Care, Burn Center, Hangang Sacred Heart Hospital, Hallym University Medical Center, College of Medicine, Hallym University, 12, Beodeunaru-ro 7-gil, Yeongdeungpo-gu, Seoul, 07247, Korea. hammerj@hallym.or.kr.
Jaechul YoonDepartment of Surgery and Critical Care, Burn Center, Hangang Sacred Heart Hospital, Hallym University Medical Center, College of Medicine, Hallym University, 12, Beodeunaru-ro 7-gil, Yeongdeungpo-gu, Seoul, 07247, Korea.
Myongjin KimDepartment of Surgery and Critical Care, Burn Center, Hangang Sacred Heart Hospital, Hallym University Medical Center, College of Medicine, Hallym University, 12, Beodeunaru-ro 7-gil, Yeongdeungpo-gu, Seoul, 07247, Korea.
Yong Suk ChoDepartment of Surgery and Critical Care, Burn Center, Hangang Sacred Heart Hospital, Hallym University Medical Center, College of Medicine, Hallym University, 12, Beodeunaru-ro 7-gil, Yeongdeungpo-gu, Seoul, 07247, Korea.
Wook ChunDepartment of Surgery and Critical Care, Burn Center, Hangang Sacred Heart Hospital, Hallym University Medical Center, College of Medicine, Hallym University, 12, Beodeunaru-ro 7-gil, Yeongdeungpo-gu, Seoul, 07247, Korea.
Dogeon YoonBurn Institutes, Hangang Sacred Heart Hospital, Hallym University Medical Center, 12, Beodeunaru-ro 7-gil, Youngdeungpo-gu, Seoul, 07247, Korea.

Funding

National Research Foundation of Korea NRF-2021R1A2C2006033
6 · The paper itself

Abstract

Acute Respiratory Distress Syndrome (ARDS) is a critical form of Acute Lung Injury (ALI), challenging clinical diagnosis and severity assessment. This study evaluates the potential utility of various hematological markers in burn-mediated ARDS, including Neutrophil-to-Lymphocyte Ratio (NLR), Mean Platelet Volume (MPV), MPV-to-Lymphocyte Ratio (MPVLR), Platelet count, and Platelet Distribution Width (PDW). Employing a retrospective analysis of data collected over 12 years, this study focuses on the relationship between these hematological markers and ARDS diagnosis and severity in hospitalized patients. The study establishes NLR as a reliable systemic inflammation marker associated with ARDS severity. Elevated MPV and MPVLR also emerged as significant markers correlating with adverse outcomes. These findings suggest these economical, routinely measured markers can enhance traditional clinical criteria, offering a more objective approach to ARDS diagnosis and severity assessment. Hematological markers such as NLR, MPV, MPVLR, Platelet count, and PDW could be invaluable in clinical settings for diagnosing and assessing ARDS severity. They offer a cost-effective, accessible means to improve diagnostic accuracy and patient stratification in ARDS. However, further prospective studies are necessary to confirm these findings and investigate their integration with other diagnostic tools in diverse clinical settings.

Indexed as

BiomarkersBurnsRespiratory Distress SyndromeSeverity of Illness IndexAdultAgedFemaleHumansLymphocytesMaleMean Platelet VolumeMiddle AgedNeutrophilsPlatelet CountRetrospective StudiesBiomarkersARDSCBCMPVNLRPlatelet

Identifiers

PMID38834610
PMCPMC11150426

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.