ArticleNature communications2024
An implantable piezoelectric ultrasound stimulator (ImPULS) for deep brain activation.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- Active devices and systems for closed-loop neuromodulation.Microsystems & nanoengineering · 2026Review
- A sonoelectric artificial meningeal device for enhanced implantable electric field ablation of glioblastoma.Scientific reports · 2026Article
- Wearable ultrasound: a review of core technologies and clinical applications in cardiovascular monitoring.Microsystems & nanoengineering · 2026Review
- Flexible bioelectronic sensors promote the advancement of wearable ultrasound technology in the medicine.Microsystems & nanoengineering · 2026Review
- Real-time 3D ultrasound in augmented reality accelerates training and narrows novice-expert performance gaps.Communications engineering · 2026Article
- Intelligent Acousto-Electrical Metamaterials (IAM) for Sound Source Detection.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- An implantable mechano-electro cascade platform synchronizes neuro-muscle repair.Nature communications · 2026Article
- Recent advances in transducers for through-tissue ultrasonic power transfer.Progress in biomedical engineering (Bristol, England) · 2026Review
- Ultrasound-Assisted multimodal neuromodulation via nanosystems.Journal of nanobiotechnology · 2026Review
- Real-Time 3D Ultrasound Imaging with an Ultra-Sparse, Low Power Architecture.Advanced healthcare materials · 2026Article
- Ultrasonic repression of TRPA1-dependent astrocyte reactivity confers neuroprotection in models of Lewy body dementia.Translational neurodegeneration · 2026Article
- Ultrasound in Women's Health: Mechanisms, Applications, and Emerging Opportunities.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- The electrical tumor microenvironment: abnormalities and opportunities.Frontiers in oncology · 2026Review
- Synergistic Anti-Cancer Therapy Through Ultrasound-Induced Piezocatalytic Therapy and Tumor Treatment Fields.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Piezo1 Mediates Ultrasound-Stimulated Dopaminergic Neuron Protection via Synaptic Vesicle Recycling and Ferroptosis Inhibition.Neuroscience bulletin · 2025Article
- Next-Generation Piezoelectric Materials in Wearable and Implantable Devices for Continuous Physiological Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Decoding paradoxical BOLD responses to transcranial ultrasound stimulation with concurrent optoacoustic magnetic resonance imaging.Science advances · 2025Article
- Design and Manufacturing of Piezoelectric Biomaterials for Bioelectronics and Biomedical Applications.Chemical reviews · 2025Review
- Topology in Biological Piezoelectric Materials.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- A wearable spatiotemporal controllable ultrasonic device with amyloid-β disaggregation for continuous Alzheimer's disease therapy.Science advances · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
16 authors.
Funding
Abstract
Precise neurostimulation can revolutionize therapies for neurological disorders. Electrode-based stimulation devices face challenges in achieving precise and consistent targeting due to the immune response and the limited penetration of electrical fields. Ultrasound can aid in energy propagation, but transcranial ultrasound stimulation in the deep brain has limited spatial resolution caused by bone and tissue scattering. Here, we report an implantable piezoelectric ultrasound stimulator (ImPULS) that generates an ultrasonic focal pressure of 100 kPa to modulate the activity of neurons. ImPULS is a fully-encapsulated, flexible piezoelectric micromachined ultrasound transducer that incorporates a biocompatible piezoceramic, potassium sodium niobate [(K,Na)NbO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.