ArticleMed (New York, N.Y.)2024
Global pattern, trend, and cross-country inequality of early musculoskeletal disorders from 1990 to 2019, with projection from 2020 to 2050.
Article in Med (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.
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Who cites it
46 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effectiveness of Physical Activity in the Management of Nonspecific Low Back Pain: A Systematic Review.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Relationship Between Serum Vitamin D Levels and Chronic Musculoskeletal Pain in Adults: A Systematic Review.Nutrients · 2024Pooled it
- Trends in the Asthma Burden Attributable to High Body Mass Index in Children Across 204 Countries and Territories, 1990-2021: An Analysis of the 2021 Global Burden of Disease Study.The Kaohsiung journal of medical sciences · 2026Article
- Quantifying inequalities and forecasting the burden of chronic kidney disease from 1990 to 2040.iScience · 2026Article
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- Evaluation of Large Language Models in Generating Physical Exercise Rehabilitation Programs for Musculoskeletal Disorders Across Multiple Clinical Scenarios.Healthcare (Basel, Switzerland) · 2026Article
- Osteoarthritis: Epidemiology, Diagnosis, and Treatment.MedComm · 2026Review
- Loneliness, traditional risk factor control, genetic predisposition, and development of musculoskeletal disorders.Rheumatology (Oxford, England) · 2026Article
- Emerging concepts in osteoarthritis and musculoskeletal diseases: Insights from the University of Debrecen Musculoskeletal Symposium 2025.Osteoarthritis and cartilage open · 2026Article
- The association between pain and diagnosis-specific long-term sickness absence at different levels of body mass index - a register-linked cohort study.BMC public health · 2026Article
- Global, Regional, and National Burden of Oral Diseases in Older Adults Aged 65 Years And Over.International dental journal · 2026Article
- Mesenchymal stem cell-derived extracellular matrix for musculoskeletal tissue regeneration.Communications biology · 2026Review
- Observational Comparative Study for Surgical Outcomes of One- or Two-Level Lumbar Fusion Surgery Between Transforaminal Lumbar Interbody Fusion and Lateral Lumbar Interbody Fusion.Journal of clinical medicine · 2026Article
- Hip Joint Synovial Cavity Thickness in Early Juvenile Idiopathic Arthritis Without Effusion: A Cross-Sectional Ultrasound Study.Journal of clinical medicine · 2026Article
- Article
- Effects of meteorological variability on the burden of musculoskeletal disorders among people aged 55 and above in the United States: a secondary analysis of the Global Burden of Disease Study 2021.Frontiers in public health · 2026Article
- New-onset renal diseases after total knee arthroplasty in patients with osteoarthritis: a multicenter retrospective cohort study.International journal of medical sciences · 2026Article
- Integrated Multiomics Analysis Identifies CDO1 as a Novel Therapeutic Target for OsteoarthritisEndocrine, metabolic & immune disorders drug targets · 2026Article
- Long-Term Trends in the Global Burden of Age-Related Macular Degeneration: Sex Differences, Aging Effects, and Future Projections in Middle-Aged and Older Adults.Ophthalmic research · 2026Article
- Rising burden of steatotic liver disease in women of childbearing age and projections to 2035.JHEP reports : innovation in hepatology · 2026Article
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Abstract
backgroundThis study aims to estimate the burden, trends, forecasts, and disparities of early musculoskeletal (MSK) disorders among individuals ages 15 to 39 years.
methodsThe global prevalence, years lived with disabilities (YLDs), disability-adjusted life years (DALYs), projection, and inequality were estimated for early MSK diseases, including rheumatoid arthritis (RA), osteoarthritis (OA), low back pain (LBP), neck pain (NP), gout, and other MSK diseases (OMSKDs).
findingsMore adolescents and young adults were expected to develop MSK disorders by 2050. Across five age groups, the rates of prevalence, YLDs, and DALYs for RA, NP, LBP, gout, and OMSKDs sharply increased from ages 15-19 to 35-39; however, these were negligible for OA before age 30 but increased notably at ages 30-34, rising at least 6-fold by 35-39. The disease burden of gout, LBP, and OA attributable to high BMI and gout attributable to kidney dysfunction increased, while the contribution of smoking to LBP and RA and occupational ergonomic factors to LBP decreased. Between 1990 and 2019, the slope index of inequality increased for six MSK disorders, and the relative concentration index increased for gout, NP, OA, and OMSKDs but decreased for LBP and RA.
conclusionsMultilevel interventions should be initiated to prevent disease burden related to RA, NP, LBP, gout, and OMSKDs among individuals ages 15-19 and to OA among individuals ages 30-34 to tightly control high BMI and kidney dysfunction.
fundingThe Global Burden of Disease study is funded by the Bill and Melinda Gates Foundation. The project is funded by the Scientific Research Fund of Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (2022QN38).
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