ArticleHepatology international2024
Hepatic-associated vascular morphological assessment to predict overt hepatic encephalopathy before TIPS: a multicenter study.
Article in Hepatology international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Risk prediction models for hepatic encephalopathy in patients with liver cirrhosis: a systematic review and meta-analysis.BMC gastroenterology · 2026Pooled it
- Risk prediction models for hepatic encephalopathy following TIPS: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Artificial Intelligence for Personalized Prediction of Post-TIPS Outcomes: Integrating Clinical, Biochemical, and Radiomics Data-A Narrative Review.Journal of clinical medicine · 2026Review
- Enhancing post-TIPS hepatic encephalopathy risk stratification: a hybrid TabPFN model leveraging radiomics, deep transfer learning features, and MELD score.Hepatology international · 2026Article
- Beyond left versus right: from puncture site selection to clinical strategy in TIPS.Hepatology international · 2026Article
- Machine learning-based risk prediction of overt hepatic encephalopathy after transjugular intrahepatic portosystemic shunt in patients with cirrhosis: a cohort study.Frontiers in medicine · 2026Article
- Management of hepatic encephalopathy following transjugular intrahepatic portosystemic shunts: Current strategies and future directions.World journal of gastroenterology · 2025Review
- Association between overt hepatic encephalopathy and liver pathology after transjugular intrahepatic portosystemic shunt creation in cirrhotic patients.Scientific reports · 2025Article
Corrections and comments
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Authors and funding
18 authors.
Funding
Abstract
backgroundTo provide patients the chance of accepting curative transjugular intrahepatic portosystemic shunt (TIPS) rather than palliative treatments for portal hypertension-related variceal bleeding and ascites, we aimed to assess hepatic-associated vascular morphological change to improve the predictive accuracy of overt hepatic encephalopathy (HE) risks.
methodsIn this multicenter study, 621 patients undergoing TIPS were subdivided into training (413 cases from 3 hospitals) and external validation datasets (208 cases from another 3 hospitals). In addition to traditional clinical factors, we assessed hepatic-associated vascular morphological changes using maximum diameter (including absolute and ratio values). Three predictive models (clinical, hepatic-associated vascular, and combined) were constructed using logistic regression. Their discrimination and calibration were compared to test the necessity of hepatic-associated vascular assessment and identify the optimal model. Furthermore, to verify the improved performance of Model
resultsThe combined model outperformed the clinical and hepatic-associated vascular models (training: 0.814, 0.754, 0.727; validation: 0.781, 0.679, 0.776; p < 0.050) and had the best calibration. Compared to previous models, Model
conclusionHepatic-associated vascular assessment improved the predictive accuracy of overt HE, ensuring curative chances by TIPS for suitable patients and providing insights for cirrhosis-related studies.
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