Evidence map›Paper›PMID 38832903›Full record

ArticleThe Journal of cell biology2024

Profilin affects microtubule dynamics via actin.

Heidi Ulrichs, Shashank Shekhar

Abstract readComment
In one paragraph

Article in The Journal of cell biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Heidi UlrichsDepartments of Physics, Cell Biology and Biochemistry, Emory University, Atlanta, GA, USA.
Shashank ShekharDepartments of Physics, Cell Biology and Biochemistry, Emory University, Atlanta, GA, USA.ORCID 0000-0003-1494-0151

Funding

MULTICOMPONENT MECHANOCHEMICAL REGULATION OF ACTIN FILAMENT END DYNAMICSR35GM143050 · NIGMS · EMORY UNIVERSITY · PI Shashank Shekhar · 2021 to 2026
$2.7M
NIGMS NIH HHS R35 GM143050NIGMS NIH HHS R35GM143050
6 · The paper itself

Abstract

Profilin binds microtubules in vitro. However, a new study by Vitriol and colleagues (https://doi.org/10.1083/jcb.202309097) now suggests that effects of profilin on microtubule dynamics in cells are indirect and result from its impact on actin dynamics rather than its direct binding to microtubules.

Indexed as

ActinsMicrotubulesProfilinsProtein BindingActinsProfilins

Identifiers

PMID38832903
PMCPMC11148468

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.