Evidence map›Paper›PMID 38832890›Full record

ArticleJournal of natural products2024

The Kavaratamides: Discovery of Linear Lipodepsipeptides from the Marine Cyanobacterium

Byeol Ryu, Evgenia Glukhov, Thaiz R Teixeira, Conor R Caffrey, Saranya Madiyan, Valsamma Joseph, Nicole E Avalon, Christopher A Leber, C Benjamin Naman, William H Gerwick

Abstract read
In one paragraph

Article in Journal of natural products, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. SPECTRE: A Multimodal Spectral Transformer for Small Molecule Annotation.Journal of chemical information and modeling · 2026
    Article
  4. Rapid Discovery of Antifungal α-Pyrone Analogs fromJournal of fungi (Basel, Switzerland) · 2026
    Article
  5. Marine natural products.Natural product reports · 2026
    Review
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Byeol RyuCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.ORCID 0000-0002-3405-2875
Evgenia GlukhovCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.
Thaiz R TeixeiraCenter for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.
Conor R CaffreyCenter for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.
Saranya MadiyanNational Centre for Aquatic Animal Health, Cochin University of Science and Technology, Kochi, Kerala 682016, India.
Valsamma JosephNational Centre for Aquatic Animal Health, Cochin University of Science and Technology, Kochi, Kerala 682016, India.
Nicole E AvalonCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.ORCID 0000-0003-3588-892X
Christopher A LeberCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.
C Benjamin NamanCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.ORCID 0000-0002-4361-506X
William H GerwickCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.ORCID 0000-0003-1403-4458

Funding

Unified Computation Tools for Natural Products ResearchR01GM107550 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI COTTRELL, GARRISON W, GERWICK, WILLIAM HENRY · 2013 to 2025
$8.2M
Development of thiophen-2-yl-phenylpyrimidines for treatment of schistosomiasisR21AI156554 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BALLATORE, CARLO, CAFFREY, CONOR · 2021 to 2022
$435k
A Genomic Approach to Discovering Novel Cathepsin Inhibitors from CyanobacteriaF32AT011475 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AVALON, NICOLE ELIZABETH · 2022 to 2024
$218k
NCCIH NIH HHS F32 AT011475NIAID NIH HHS R21 AI156554NIGMS NIH HHS R01 GM107550
6 · The paper itself

Abstract

Kavaratamide A (

Indexed as

CyanobacteriaDepsipeptidesChromatography, High Pressure LiquidDrug Screening Assays, AntitumorHumansIndiaMarine BiologyMolecular StructureNuclear Magnetic Resonance, BiomolecularDepsipeptides

Identifiers

PMID38832890
PMCPMC11217931

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.