Evidence map›Paper›PMID 38832498›Full record

SynthesisRenal failure2024

Association between the gut microbiota and diabetic nephropathy: a two-sample Mendelian randomization study.

Wenjie Dong, Qiuyu Li, Lei Chen, Hui Tang, Kun Tu, Li Luo, Longyang Jiang, Yilan Huang

Abstract readMeta-Analysis
In one paragraph

Synthesis in Renal failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenjie DongDepartment of Pharmacy, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Qiuyu LiDepartment of Pharmacy, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Lei ChenDepartment of Pharmacy, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Hui TangDepartment of Pharmacy, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Kun TuDepartment of Pharmacy, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Li LuoDepartment of Pharmacy, West China Second Hospital of Sichuan University, Chengdu, Sichuan, China.
Longyang JiangDepartment of Pharmacy, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Yilan HuangDepartment of Pharmacy, The Affiliated Hospital of Southwest Medical University, Luzhou, China.ORCID 0009-0005-1949-6530

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous studies have revealed a correlation between the risk of developing diabetic nephropathy (DN) and the gut microbiota (GM) composition. However, it remains uncertain whether the GM composition causes DN. We aimed to explore any potential causal links between the GM composition and the risk of developing DN. A meta-analysis conducted by the MiBioGen consortium of the largest genome-wide association study (GWAS) provided aggregated data on the GM. DN data were obtained from the IEU database. The inverse-variance weighting (IVW) method was employed as the primary analytical approach. The IVW analysis indicated that genus

Indexed as

Diabetic NephropathiesGastrointestinal MicrobiomeGenome-Wide Association StudyMendelian Randomization AnalysisHumanscausal effectDiabetic nephropathygut microbiotaMendelian randomizationsingle nucleotide polymorphism

Identifiers

PMID38832498
PMCPMC11151794

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.