Evidence map›Paper›PMID 38832480›Full record

ReviewJournal of Korean medical science2024

Lessons From the Household Humidifier Disinfectant Tragedy (HHDT) With Focus on the Chemical Poisoning Surveillance System: Review and Recommendation.

Dong-Uk Park, Thomas H Gassert, Kyung Ehi Zoh, Dong Young Lee, Fabrizio Sesana, Soyoung Park, Seong-Yong Yoon

Abstract readReview
In one paragraph

Review in Journal of Korean medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dong-Uk ParkDepartment of Environmental Health, Korea National Open University, Seoul, Korea. pdw545@gmail.com.ORCID https://orcid.org/0000-0003-3847-7392
Thomas H GassertDepartment of Environmental Health, Harvard Chan School of Public Health, Boston, MA, USA.ORCID https://orcid.org/0000-0002-2422-0775
Kyung Ehi ZohDepartment of Environmental Health, Graduate School of Public Health, Seoul National University, Seoul, Korea.ORCID https://orcid.org/0000-0002-2821-070X
Dong Young LeeEnvironment and Labor Division, National Assembly Research Service, Seoul, Korea.ORCID https://orcid.org/0000-0001-6286-7476
Fabrizio SesanaMilano Poison Center and Clinical Pharmacology, Milano, Italy.ORCID https://orcid.org/0000-0002-6293-1850
Soyoung ParkDepartment of Occupational and Environmental Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-2163-5892
Seong-Yong YoonDepartment of Occupational and Environmental Medicine, Soonchunhyang University Gumi Hospital, School of Medicine, Soonchunhyang University, Gumi, Korea.ORCID https://orcid.org/0000-0003-3297-5841

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLessons learned from the Household Humidifier Disinfectant Tragedy (HHDT) in Korea, which poisoned thousands of citizens over a period of years, necessitated an examination of national poison prevention and surveillance systems. The objectives of this study are to identify essential changes needed in chemical poisoning prevention regulations and surveillance systems for effective poison control by comparing recent trends in international poison control center (PCC) operations, and to delineate the critical elements for establishing a state-of-the-art poison control surveillance system in Korea based on recent advances in PCCs with toxicovigilance.

methodsA comprehensive review of Korea's regulatory and surveillance systems for chemical health hazards, with a focus on household products under the HHDT, was conducted. A review of toxicovigilance systems in major countries shows that creating an effective national PCC requires key elements: a centralized database of toxic substances and poisoning cases, mandatory or voluntary reporting of poisoning cases, real-time alerts, collaboration among health organizations, and targeted follow-up of poisoned individuals.

resultsSignificant deficiencies in Korea's legislation, toxicological data management, and poisoning surveillance systems, explained the inadequate response of the Korean government to the HHDT for nearly 17 years until the end of 2011. Based on a review of PCC toxicovigilance systems in major countries, a national framework with five core components is recommended for establishing a modern comprehensive Korea PCC system with toxicovigilance capacity. The core components include establishment of a centralized database of toxic substances information and clinical poisoning cases, implementation of mandatory or permissive reporting of poisoning cases, real-time alert mechanisms, collaborative systems among health-related organizations, and clinical follow-up of poisoned sub-groups.

conclusionA rationale and framework for a state-of-the-art national Korean PCC with toxicovigilance is justified and offered. This proposed system could assist neighboring countries in establishing their own sophisticated, globally integrated PCC networks.

Indexed as

DisinfectantsHumidifiersPoisoningHumansPoison Control CentersRepublic of KoreaDisinfectantsChemical PoisoningHousehold Humidifier Disinfectant Tragedy (HHDT)Poison Control Center (PCC)Toxicovigilance Systems

Identifiers

PMID38832480
PMCPMC11147787

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.