ArticleClinical interventions in aging2024
The Validity of Muscle Ultrasound in the Diagnostic Workup of Sarcopenia Among Older Adults: A Scoping Review.
Article in Clinical interventions in aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07530029 (Multimodal Approach to Sarcopenia and Its Prognostic Impact in Older Patients Hospitalized for Acute Heart Failure), which is not on this map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Multimodal Approach to Sarcopenia and Its Prognostic Impact in Older Patients Hospitalized for Acute Heart Failure (MUSICA Study).
Who cites it
15 citing papers in PubMed.
- Sarcopenia in Inflammatory Bowel Disease: Prevalence, Mechanisms, Detection, Adverse Clinical Impact and Targetable Care Gaps-A Narrative Review Supported by a Structured Literature Search.Life (Basel, Switzerland) · 2026Review
- Identification of ultrasound predictors and development of a diagnostic scoring system for sarcopenia using LASSO regression: a cross-sectional study.Scientific reports · 2026Article
- Muscle ultrasound and shear wave elastography for screening sarcopenia in patients undergoing maintenance hemodialysis: a prospective study.Frontiers in medicine · 2026Article
- Screening Utility of Lower Limb Muscle Ultrasound for Sarcopenia in COPD Patients.International journal of chronic obstructive pulmonary disease · 2026Article
- Bridging assessment, biomarkers, and interventions: progress in muscle health research.Frontiers in rehabilitation sciences · 2026Article
- Association between urinary incontinence and sarcopenic obesity among middle-aged and older Brazilian women.PeerJ · 2026Article
- Determination of Ultrasound Reference Values for Diagnosing Low Muscle Mass in Older Chinese Adults.Journal of cachexia, sarcopenia and muscle · 2025Article
- Establishing Ultrasound Thresholds for Sarcopenia Diagnosis in Older Brazilian Adults.Muscles (Basel, Switzerland) · 2025Article
- Qualitative and quantitative ultrasonographic assessment of muscle and its association with comprehensive geriatric assessment results among older patients scheduled for abdominal surgery.Journal of ultrasonography · 2025Article
- Normative data of ultrasound quadriceps rectus femoris geometric values. The ECOSARC-2 Study.The journal of nutrition, health & aging · 2025Article
- Article
- Diagnostic value of different skeleton muscles in elderly COPD patients with sarcopenia.European journal of medical research · 2025Article
- Article
- Quadriceps muscle thickness as measured by point-of-care ultrasound is associated with hospital length of stay among hospitalised older patients.Age and ageing · 2025Article
- Discriminative Ability and Associations of Sarcopenia Using Point-of-Care Ultrasound with Functional, Mobility and Frailty Status in Older Inpatients.Journal of clinical medicine · 2025Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Muscle ultrasound has emerged as a promising method in the diagnostic work-up of sarcopenia. The objective of this scoping review was to explore the validity of muscle ultrasound against the latest sarcopenia definitions among older adults. Methods: We adhered to the PRISMA guidelines for scoping reviews. A systematic search of databases was performed by two independent reviewers. All articles comparing the performance of ultrasound to an internationally acknowledged sarcopenia definition among older adults (≥60 years) and published between 2019/01/01 (the year updated sarcopenia definitions were introduced) and 2023/11/15 were included. Data were extracted and collated by muscle and muscle parameters. Results: Out of 2290 articles screened, six studies comprising 24 validity tests among a total of 1619 older adults (mean age 74.1 years, 52.2% female) were included. The validity tests investigated the rectus femoris (n = 7), biceps brachii (n = 5), gastrocnemius medialis (n = 4), tibialis anterior (n = 4), soleus (n = 3), and rectus abdominis (n = 1). The parameter muscle thickness (MT) (n = 14) was most commonly measured. The latest European and Asian sarcopenia definitions (EWGSOP2, AWGS2) were applied as reference standards in four validity tests each. None of the studies used the Sarcopenia Definition and Outcome Consortium (SDOC) criteria. The highest area under the curve AUC (0.92, 95% confidence interval [CI] 0.89-0.94) was found for the muscle thickness of the rectus femoris muscle. Due to substantial heterogeneity among the studies, pooling of data using a meta-analytic approach was not feasible. Conclusion: Limited number of studies have examined the validity of muscle ultrasound for diagnosing sarcopenia based on recent definitions among older adults. Thereby, muscle thickness of the rectus femoris showed promising results regarding validity. Further studies are needed to investigate the validity of key muscles and to validate muscle ultrasound among older hospitalized patients.
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