Evidence map›Paper›PMID 38831962›Full record

ArticleIDCases2024

Herpes simplex viral encephalitis with acute memory impairment and low cellular cerebrospinal fluid: A case report with systematic review literature.

Mostafa Mahmoud Meshref, Abdullah Ashraf Hamad, Amira Mohammed Taha, Yahia Nabil, Ahmed Hassan, Ahmed Samir Farw, Mohamed Elmasry, Abdulqadir J Nashwan

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in IDCases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mostafa Mahmoud MeshrefNeurology Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Abdullah Ashraf HamadFaculty of Medicine, Menoufia University, Menoufia, Egypt.
Amira Mohammed TahaFaculty of Medicine, Fayoum University, Fayoum, Egypt.
Yahia NabilFaculty of Medicine, Zagazig University, Egypt.
Ahmed HassanNeurology Department, Tawam Hospital, Al-Ain, United Arab Emirates.
Ahmed Samir FarwNeurology Department, Tawam Hospital, Al-Ain, United Arab Emirates.
Mohamed ElmasryAlexandria Medical School, Alexandria University, Egypt.
Abdulqadir J NashwanHamad Medical Corporation (HMC), Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes simplex encephalitis (HSVE) is a potentially fatal infectious central nervous system (CNS) disorder. Thus, early detection is critical in determining the case's fate. Clinical history and examination, brain computed tomography, dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), and lumbar puncture have been used to establish a diagnosis. This report describes a case of HSVE with hypocellular cerebrospinal fluid (CSF) and an uncommon form of memory impairment. However, MRI results were consistent with HSVE, and CSF PCR tested positive for HSV-1 DNA that responded to treatment. We routinely advise patients to begin antiviral therapy as soon as possible to avoid complications.

Indexed as

Case reportCerebrospinal fluidHerpes simplex virusMemory affectionPolymerase chain reaction

Identifiers

PMID38831962
PMCPMC11144719

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.