Evidence map›Paper›PMID 38831883›Full record

ReviewFrontiers in pharmacology2024

Better together: nanoscale co-delivery systems of therapeutic agents for high-performance cancer therapy.

Liyan Sun, Zhe Li, Jinshuai Lan, Ya Wu, Tong Zhang, Yue Ding

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liyan Sun *School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zhe Li *School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jinshuai Lan *School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Ya Wu *School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Tong ZhangSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yue DingSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Combination therapies can enhance the sensitivity of cancer to drugs, lower drug doses, and reduce side effects in cancer treatment. However, differences in the physicochemical properties and pharmacokinetics of different therapeutic agents limit their application. To avoid the above dilemma and achieve accurate control of the synergetic ratio, a nanoscale co-delivery system (NCDS) has emerged as a prospective tool for combined therapy in cancer treatment, which is increasingly being used to co-load different therapeutic agents. In this study, we have summarized the mechanisms of therapeutic agents in combination for cancer therapy, nanoscale carriers for co-delivery, drug-loading strategies, and controlled/targeted co-delivery systems, aiming to give a general picture of these powerful approaches for future NCDS research studies.

Indexed as

cancercombined therapycontrolled/targeted deliverydrug-loading strategiesnanoscale co-delivery system

Identifiers

PMID38831883
PMCPMC11144913

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.