Evidence map›Paper›PMID 38831822›Full record

ArticleHeliyon2024

Ameliorative effect of licorice extract against the detrimental effect of glyphosate-based pesticide: Toxicity and health.

Ahmed N Elkattan, Sayad El-Saadany, Mohamed Azzazy, Tarek M Okda, Maha Mamdouh, Osama Ahmed, Ali H El-Far, Manar ElKhayat, Ghadeer M Albadrani, Muath Q Al-Ghadi and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ahmed N ElkattanInstitute of Graduate Studies and Environmental Research, DamanhourUniversity, 22511, Damanhour, Egypt.
Sayad El-SaadanyBiochemistry Department, Faculty of Agriculture, Zagazig University, 44511, Zagazig, Egypt.
Mohamed AzzazyPlant Ecology, Institute of Desert Studies, Sadat City University, 32897, El Sadat City, Egypt.
Tarek M OkdaBiochemistry Department, Faculty of Pharmacy, Damanhur University, 22511, Damanhour, Egypt.
Maha MamdouhDepartment of Physiology, Faculty of Veterinary Medicine, Benha University, 13736, Mushtuhur, Toukh, Qalioubia, Egypt.
Osama AhmedDepartment of Anatomy and Embryology, Faculty of Veterinary Medicine, Benha University, 13736, Mushtuhur, Toukh, Qalioubia, Egypt.
Ali H El-FarDepartment of Biochemistry, Faculty of Veterinary Medicine, Damanhour University, 22511, Damanhour, Egypt.
Manar ElKhayatDepartment of Bacteriology, Immunology and Mycology, Faculty of Veterinary Medicine, Benha University, 13736, Mushtuhur, Toukh, Qalioubia, Egypt.
Ghadeer M AlbadraniDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University, 84428, Riyadh, 11671, Saudi Arabia.
Muath Q Al-GhadiDepartment of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia.
Mohamed M Abdel-DaimDepartment of Pharmaceutical Sciences, Pharmacy Program, Batterjee Medical College, P.O. Box 6231, Jeddah, 21442, Saudi Arabia.
Hala El DaousFaculty of Veterinary Medicine, Benha University, 13736, Mushtuhur, Toukh, Qalioubia, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study sheds the light on the potential of licorice (Glycyrrhiza glabra) root aqueous extract as a cornerstone for mitigating and detoxifying the residues of the widely used agricultural Glyphosate-based pesticides (GBPs). This study examined the GBPs toxic effects on kidney, liver, thyroid functions, and apoptosis using 50 adult male albino rats. All rats were divided into 5 groups, with 10 each. Control: served as untreated rats. GBP: rats were treated with 1 mL glyphosate solution 24 % orally for three weeks. The glyphosate-treated rats were gavaged with licorice root aqueous extractsolution (100, 200, and 300 mg/mLdistilled water, respectively) daily for three weeks. Licorice root aqueous extract solution (300 mg/mL distilled water) yielded notable reductions in liver, kidney enzymes, albumin, and AFP levels within the serum. Immunological tests, including immunohistochemical evaluations of caspase-3 and TNF-

Indexed as

AntioxidantApoptosisGlyphosate-based pesticideLicorice (Glycyrrhiza glabra)Toxicity

Identifiers

PMID38831822
PMCPMC11145546

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.