Evidence map›Paper›PMID 38831775›Full record

ArticleFrontiers in genetics2024

Keratin 19 (Krt19) is a novel marker gene for epicardial cells.

Juan Xu, Yiting Deng, Guang Li

Abstract read
In one paragraph

Article in Frontiers in genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Juan XuDepartment of Cell Biology, Center for Integrative Organ Systems, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Yiting DengDepartment of Cell Biology, Center for Integrative Organ Systems, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Guang LiDepartment of Cell Biology, Center for Integrative Organ Systems, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.

Funding

Generation of four-chambered hearts through organoid fusionsDP2HL163745 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LI, GUANG · 2021 to 2024
$2.4M
Cellular and Molecular Mechanisms of Atrial Cardiomyocyte Lineage Commitment R00HL133472 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LI, GUANG · 2019 to 2021
$750k
NHLBI NIH HHS DP2 HL163745NHLBI NIH HHS R00 HL133472
6 · The paper itself

Abstract

Epicardial cells regulate heart growth by secreting numerous growth factors and undergoing lineage specification into other cardiac lineages. However, the lack of specific marker genes for epicardial cells has hindered the understanding of this cell type in heart development. Through the analysis of a cardiac single cell mRNA sequencing dataset, we identified a novel epicardial gene named

Indexed as

ablationDTAepicardial cellKRT19lineage tracingWT1

Identifiers

PMID38831775
PMCPMC11145414

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.