Evidence map›Paper›PMID 38831624›Full record

ArticleCell proliferation2024

MicroRNA-3061 downregulates the expression of PAX7/Wnt/Ca

Te Liu, Yichao Wen, Zeyu Cui, Haiyang Chen, Jiajia Lin, Jianghong Xu, Danping Chen, Ying Zhu, Zhihua Yu, Chunxia Wang and 1 more

Abstract read
In one paragraph

Article in Cell proliferation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. METTL3-mediated mMolecular cancer · 2026
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Te LiuShanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.ORCID https://orcid.org/0000-0003-3976-3489
Yichao WenShanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zeyu CuiShanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Haiyang ChenShanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jiajia LinShanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jianghong XuDepartment of Gynaecology, Jingan Hospital of Traditional Chinese Medicine, Shanghai, China.
Danping ChenDepartment of Gynaecology, Jingan Hospital of Traditional Chinese Medicine, Shanghai, China.
Ying ZhuDepartment of Gynaecology, Jingan Hospital of Traditional Chinese Medicine, Shanghai, China.
Zhihua YuShanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Chunxia WangDepartment of Reproductive Medicine, Henan Province Hospital of Traditional Chinese Medicine, Henan, China.
Bimeng ZhangDepartment of Acupuncture, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Funding

Clinical Research Special Fund of Shanghai Municipal Health Commission 202240223National Natural Science Foundation of China 81973899National Natural Science Foundation of China 82274569
6 · The paper itself

Abstract

The in-depth mechanisms of microRNA regulation of premature ovarian failure (POF) remain unclear. Crispr-cas9 technology was used to construct transgenic mice. The qPCR and Western blot was used to detect the expression level of genes. H&E staining were used to detect ovarian pathological phenotypes. We found that the expression levels of microRNA-3061 were significantly higher in ovarian granulosa cells (OGCs) of POF mouse models than in controls. The miR-3061

Indexed as

Down-RegulationGranulosa CellsMicroRNAsPAX7 Transcription FactorPrimary Ovarian InsufficiencyWnt Signaling PathwayAnimalsCalcium SignalingFemaleHumansMiceMice, TransgenicMicroRNAsPAX7 Transcription Factor

Identifiers

PMID38831624
PMCPMC11533063

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.