ArticleNature methods2024
Detailed mapping of the complex fiber structure and white matter pathways of the chimpanzee brain.
Article in Nature methods, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience.Advanced healthcare materials · 2026Pooled it
- Bioinspired hierarchical fibre bundles from microfluidics for nerve regeneration.Bioactive materials · 2026Article
- Multi-dimensional diffusion MRI at ultra-high gradient strength for mapping axonal architecture and microstructure in the primate brain.bioRxiv : the preprint server for biology · 2026Article
- Abnormal signal transmission in white matter revealed by resting-state communication connectivity in Alzheimer's disease: A comprehensive cross-sectional and longitudinal study.Translational psychiatry · 2026Article
- Ultra-high gradient connectomics and microstructure MRI scanner for imaging of human brain circuits across scales.Nature biomedical engineering · 2026Article
- Evolutionary Convergence of the Arcuate Fasciculus in Marmosets and Humans.bioRxiv : the preprint server for biology · 2025Article
- 7 Tesla multimodal MRI dataset of ex-vivo human brain.Scientific data · 2025Article
- Long arcuate fascicle in wild and captive chimpanzees as a potential structural precursor of the language network.Nature communications · 2025Article
- The inferior fronto-occipital fasciculus: bridging phylogeny, ontogeny and functional anatomy.Brain : a journal of neurology · 2025Review
- The Chimpanzee Brainnetome Atlas reveals distinct connectivity and gene expression profiles relative to humans.Innovation (Cambridge (Mass.)) · 2025Article
- Translational network neuroscience: Nine roadblocks and possible solutions.Network neuroscience (Cambridge, Mass.) · 2025Article
- Comparative Analysis of Human-Chimpanzee Divergence in Brain Connectivity and its Genetic Correlates.bioRxiv : the preprint server for biology · 2024Article
- Brain structure and function: a multidisciplinary pipeline to study hominoid brain evolution.Frontiers in integrative neuroscience · 2023Article
- Evolutionary signatures in deep white matter architecture: A comparative study of humans and chimpanzees.Imaging neuroscience (Cambridge, Mass.)Article
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Authors and funding
18 authors.
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Abstract
Long-standing questions about human brain evolution may only be resolved through comparisons with close living evolutionary relatives, such as chimpanzees. This applies in particular to structural white matter (WM) connectivity, which continuously expanded throughout evolution. However, due to legal restrictions on chimpanzee research, neuroscience research currently relies largely on data with limited detail or on comparisons with evolutionarily distant monkeys. Here, we present a detailed magnetic resonance imaging resource to study structural WM connectivity in the chimpanzee. This open-access resource contains (1) WM reconstructions of a postmortem chimpanzee brain, using the highest-quality diffusion magnetic resonance imaging data yet acquired from great apes; (2) an optimized and validated method for high-quality fiber orientation reconstructions; and (3) major fiber tract segmentations for cross-species morphological comparisons. This dataset enabled us to identify phylogenetically relevant details of the chimpanzee connectome, and we anticipate that it will substantially contribute to understanding human brain evolution.
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