Evidence map›Paper›PMID 38830962›Full record

Trial reportScientific reports2024

Proprietary alpha-amylase inhibitor formulation from white kidney bean (Phaseolus vulgaris L.) promotes weight and fat loss: a 12-week, double-blind, placebo-controlled, randomized trial.

Ralf Jäger, Sidney Abou Sawan, Martin Purpura, Barbara Grube, Yvette Röske, Patricia De Costa, Pee-Win Chong

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02930668 (Double-blind, Randomised, Placebo-controlled Study to Evaluate Benefit of Glucosanol™ in Reducing Body Weight in Overweight and Moderately Obese Subjects), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02930668 nacompletednot on this map

Double-blind, Randomised, Placebo-controlled Study to Evaluate Benefit of Glucosanol™ in Reducing Body Weight in Overweight and Moderately Obese Subjects

TypeinterventionalSponsorInQpharm GroupRan2016 to 2016Enrolled90ConditionsOverweight and ObesityArmsGlucosanol 350mg, Glucosanol 500mg, Placebo
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Therapeutic Potential of White Kidney Beans (Foods (Basel, Switzerland) · 2025
    Review
  5. Article
  6. Review
  7. Evaluation ofFoods (Basel, Switzerland) · 2025
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ralf JägerIncrenovo LLC, Whitefish Bay, WI, USA. ralf.jaeger@increnovo.com.
Sidney Abou SawanIovate Health Sciences International, Oakville, ON, Canada.
Martin PurpuraIncrenovo LLC, Whitefish Bay, WI, USA.
Barbara GrubePractice for General Medicine, Berlin, Germany.
Yvette RöskeAnalyze and Realize GmbH, Berlin, Germany.
Patricia De CostaInQpharm Consumer Health Ltd., Abertillery, UK.
Pee-Win ChongInQpharm Consumer Health Ltd., Abertillery, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

White kidney bean (Phaseolus vulgaris L.) extracts can aid weight management by reducing calorie intake from complex carbohydrates through alpha-amylase inhibition. We examined the impact of a proprietary aqueous extract from whole dried white kidney beans standardized by its alpha-amylase inhibitor activity (Phase 2 white kidney bean extract (WKBE)) on weight management in subjects with overweight and moderate obesity. In a randomized, double-blind, placebo-controlled fashion, 81 participants completed the study and ingested either a high dose of Phase 2 (1000 mg, WKBE HIGH), a low dose (700 mg, WKBE LOW), or a matching placebo (microcrystalline cellulose, PLA) three times a day, 30 min before meals, for 12 weeks during a calorie restricted diet. In a dose-dependent manner, Phase 2 significantly reduced body weight, fat mass, BMI, waist, hip and in the WKBE HIGH group thigh circumference. Phase 2 is an effective and safe supplement aiding weight and fat loss. ClinicalTrials.gov identifier NCT02930668.

Indexed as

PhaseolusPlant ExtractsAdultalpha-AmylasesDouble-Blind MethodFemaleHumansMaleMiddle AgedObesityOverweightPlant LectinsWeight Lossalpha-amylase inhibitor, Phaseolus vulgarisalpha-AmylasesPlant ExtractsPlant LectinsBMIBody shapingFat massObesityWeight management

Identifiers

PMID38830962
PMCPMC11148185

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.