Evidence map›Paper›PMID 38830206›Full record

ReviewJournal of basic and clinical physiology and pharmacology2024

Interplay between male gonadal function and overall male health.

Vincenzo Asero, Carlo Maria Scornajenghi, Salvatore Iaconis, Enrico Sicignano, Alfonso Falcone, Fabrizio Dinacci, Giovanni Pagano, Dalila Carino, Roberta Corvino, Anas Tresh

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of basic and clinical physiology and pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vincenzo AseroDepartment of Maternal Infant and Urologic Sciences, 9311 University of Rome La Sapienza , Rome, Lazio, Italy.
Carlo Maria ScornajenghiDepartment of Maternal Infant and Urologic Sciences, 9311 University of Rome La Sapienza , Rome, Lazio, Italy.
Salvatore IaconisDepartment of Neuroscience and Reproductive and Odontostomatological Sciences, 165474 Federico II University Hospital , Napoli, Italy.
Enrico SicignanoDepartment of Neuroscience and Reproductive and Odontostomatological Sciences, 165474 Federico II University Hospital , Napoli, Italy.ORCID https://orcid.org/0000-0003-2725-8530
Alfonso FalconeDepartment of Neurosciences, Science of Reproduction and Odontostomatology, 9307 University of Naples Federico II , Napoli, Campania, Italy.
Fabrizio DinacciDepartment of Neuroscience and Reproductive and Odontostomatological Sciences, 165474 Federico II University Hospital , Napoli, Campania, Italy.
Giovanni PaganoDepartment of Neurosciences, Science of Reproduction and Odontostomatology, 9307 University of Naples Federico II , Napoli, Italy.
Dalila CarinoDepartment of Maternal Infant and Urologic Sciences, 9311 University of Rome La Sapienza , Rome, Italy.
Roberta CorvinoDepartment of Maternal Infant and Urologic Sciences, 9311 University of Rome La Sapienza , Rome, Italy.
Anas TreshDepartment of Urology, 10624 Stanford University School of Medicine , Stanford, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The process-of-male reproduction is intricate, and various medical conditions-have the potential to disrupt spermatogenesis. Moreover, infertility in males can serve as an indicator of-potential future health issue. Numerous conditions with systemic implications have been identified, encompassing genetic factors (such as Klinefelter Syndrome), obesity, psychological stress, environmental factors, and others. Consequently, infertility assessment-presents an opportunity for comprehensive health counseling, extending-beyond discussions about reproductive goals. Furthermore, male infertility has been suggested as a harbinger of future health problems, as poor semen quality and a diagnosis of-male infertility are associated with an increased risk of hypogonadism, cardiometabolic disorders, cancer, and even mortality. This review explores the existing-literature on the relationship between systemic illnesses and male fertility, impacting both clinical-outcomes and semen parameters. The majority of the literature analyzed, which compared gonadal function with genetic, chronic, infectious or tumoral diseases, confirm the association between overall male health and infertility.

Indexed as

Infertility, MaleAnimalsHumansHypogonadismMaleMen's HealthSemen AnalysisSpermatogenesisgonadal functioninfertilitymale

Identifiers

PMID38830206

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.