Evidence map›Paper›PMID 38830095›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Developmental hearing loss-induced perceptual deficits are rescued by genetic restoration of cortical inhibition.

Samer Masri, Todd M Mowery, Regan Fair, Dan H Sanes

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Hearing and early life adversity: effects of developmental stress on sensory processing.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  3. Article
  4. Developmental and Early-Life Stress-Induced Effects on 5-HTbioRxiv : the preprint server for biology · 2025
    Article
  5. Developmental hearing loss-induced perceptual deficits are rescued by genetic restoration of cortical inhibition.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Samer MasriCenter for Neural Science, New York University, New York, NY 10003.ORCID 0000-0002-5448-7446
Todd M MoweryDepartment of Otolaryngology, Rutgers, New Brunswick, NJ 08901.
Regan FairCenter for Neural Science, New York University, New York, NY 10003.
Dan H SanesCenter for Neural Science, New York University, New York, NY 10003.ORCID 0000-0002-3783-6165

Funding

Rescue of cortical inhibitory synapses following developmental hearing lossR01DC011284 · NIDCD · NEW YORK UNIVERSITY · PI SANES, DAN HARVEY · 2011 to 2022
$5.4M
Genetic rescue of a developmental hearing loss-induced spectral processing deficitF32DC020659 · NIDCD · NEW YORK UNIVERSITY · PI MASRI, SAMER · 2022 to 2024
$218k
HHS | National Institutes of Health (NIH) 5F32DC020659HHS | National Institutes of Health (NIH) DC011284NIDCD NIH HHS F32 DC020659NIDCD NIH HHS R01 DC011284
6 · The paper itself

Abstract

Even a transient period of hearing loss during the developmental critical period can induce long-lasting deficits in temporal and spectral perception. These perceptual deficits correlate with speech perception in humans. In gerbils, these hearing loss-induced perceptual deficits are correlated with a reduction of both ionotropic GABA

Indexed as

Auditory CortexGerbillinaeHearing LossAnimalsAuditory PerceptionGenetic VectorsGlutamate DecarboxylaseParvalbuminsPyramidal CellsReceptors, GABA-AReceptors, GABA-BGlutamate Decarboxylaseglutamate decarboxylase 2ParvalbuminsReceptors, GABA-AReceptors, GABA-Bauditory cortexcritical periodhearing lossinhibitionparvalbumin

Identifiers

PMID38830095
PMCPMC11181144

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.