Evidence map›Paper›PMID 38829896›Full record

SynthesisPloS one2024

Prevalence of cognitive impairment and its predictors among chronic kidney disease patients: A systematic review and meta-analysis.

Jialing Zhang, Leiyun Wu, Peixin Wang, Yajing Pan, Xingtong Dong, Linpei Jia, Aihua Zhang

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Association Between Frailty and Cognitive Impairment in Chronic Kidney Disease: A Systematic Review and Meta-Analysis.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2026
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  18. Effect of haemodialysis on the brain and heart assessed using multiparametric MRI.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jialing ZhangDepartment of Nephrology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Leiyun WuDepartment of Nephrology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Peixin WangDepartment of Nephrology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Yajing PanDepartment of Nephrology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Xingtong DongDepartment of Nephrology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Linpei JiaDepartment of Nephrology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Aihua ZhangDepartment of Nephrology, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID 0000-0003-4044-9227

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCognitive impairment (CI) is common among patients with chronic kidney disease (CKD), and is associated with a poor prognosis. We assessed the prevalence and associated factors of CI in patients with CKD.

methodsA systematic review and meta-analysis were conducted by searching PubMed, Embase, and the Web of Science through December 1, 2023. Random effects models were performed with subgroup analyses to further explore the heterogeneity.

results50 studies involving 25,289 CKD patients were included. The overall prevalence of CI was 40% (95% confidence interval 33-46). The pooled prevalence of CI was relatively higher in CKD patients from Africa (58%), Asia (44%) and America (37%). Attention and executive dysfunction appeared to be the most common manifestations. The prevalence of CI was higher among patients with hemodialysis (53%) and peritoneal dialysis (39%) than those without dialysis (32%) and post-kidney transplanted (26%). In addition, advanced age, the presence of diabetes and hypertension might increase the risk of CI in CKD patients.

conclusionsPeople with CKD have a high prevalence of CI, especially in patients with hemodialysis. An early and comprehensive screening for CI in CKD patients is needed to improve clinical outcomes.

trial registrationRegistration number: PROSPERO (CRD42023412864).

Indexed as

Cognitive DysfunctionRenal Insufficiency, ChronicHumansPrevalenceRenal DialysisRisk Factors

Identifiers

PMID38829896
PMCPMC11146742

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.