Evidence map›Paper›PMID 38829895›Full record

ArticlePLoS neglected tropical diseases2024

The macroeconomic impact of a dengue outbreak: Case studies from Thailand and Brazil.

Kinga Marczell, Elvis García, Julie Roiz, Rameet Sachdev, Philip Towle, Jing Shen, Rosarin Sruamsiri, Bruna Mendes da Silva, Riona Hanley

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Economic burden of dengue in Puerto Rico, 2010-2023.Infectious diseases of poverty · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kinga MarczellEvidera, Budapest, Hungary.ORCID 0000-0002-1714-7581
Elvis GarcíaTakeda International AG, Zürich, Switzerland.
Julie RoizEvidera, London, United Kingdom.
Rameet SachdevEvidera, Bethesda, Maryland, United States of America.
Philip TowleTakeda Pharmaceuticals International AG, Singapore.
Jing ShenTakeda International AG, Zürich, Switzerland.
Rosarin SruamsiriTakeda Thailand Ltd, Bangkok, Thailand.
Bruna Mendes da SilvaTakeda Pharmaceuticals Brazil, São Paulo, Brazil.
Riona HanleyTakeda International AG, Zürich, Switzerland.

Funding

Takeda
6 · The paper itself

Abstract

backgroundDengue is spreading in (sub)tropical areas, and half of the global population is at risk. The macroeconomic impact of dengue extends beyond healthcare costs. This study evaluated the impact of dengue on gross domestic product (GDP) based on approaches tailored to two dengue-endemic countries, Thailand and Brazil, from the tourism and workforce perspectives, respectively.

findingsBecause the tourism industry is a critical economic sector for Thailand, lost tourism revenues were estimated to analyze the impact of a dengue outbreak. An input-output model estimated that the direct effects (on international tourism) and indirect effects (on suppliers) of dengue on tourism reduced overall GDP by 1.43 billion US dollars (USD) (0.26%) in the outbreak year 2019. The induced effect (reduced employee income/spending) reduced Thailand's GDP by 375 million USD (0.07%). Overall, lost tourism revenues reduced Thailand's GDP by an estimated 1.81 billion USD (0.33%) in 2019 (3% of annual tourism revenue). An inoperability input-output model was used to analyze the effect of workforce absenteeism on GDP due to a dengue outbreak in Brazil. This model calculates the number of lost workdays associated with ambulatory and hospitalized dengue. Input was collected from state-level epidemiological and economic data for 2019. An estimated 22.4 million workdays were lost in the employed population; 39% associated with the informal sector. Lost workdays due to dengue reduced Brazil's GDP by 876 million USD (0.05%).

conclusionsThe economic costs of dengue outbreaks far surpass the direct medical costs. Dengue reduces overall GDP and inflicts national economic losses. With a high proportion of the population lacking formal employment in both countries and low income being a barrier to seeking care, dengue also poses an equity challenge. A combination of public health measures, like vector control and vaccination, against dengue is recommended to mitigate the broader economic impact of dengue.

Indexed as

DengueDisease OutbreaksBrazilGross Domestic ProductHumansThailandTourism

Identifiers

PMID38829895
PMCPMC11175482

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.