Evidence map›Paper›PMID 38829859›Full record

SynthesisPloS one2024

Perceived stigma and depression among the HIV-positive adult people in Ethiopia: A systematic review and meta-analysis.

Fikreab Desta, Demisu Zenbaba, Biniyam Sahiledengle, Yohannes Tekalegn, Demelash Woldeyohannes, Daniel Atlaw, Fikadu Nugusu, Lemlem Daniel Baffa, Degefa Gomora, Girma Beressa

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fikreab DestaDepartment of Public Health, School of Health Sciences, Madda Walabu University, Robe, Oromia, Ethiopia.ORCID 0000-0002-9706-3942
Demisu ZenbabaDepartment of Public Health, School of Health Sciences, Madda Walabu University, Robe, Oromia, Ethiopia.
Biniyam SahiledengleDepartment of Public Health, School of Health Sciences, Madda Walabu University, Robe, Oromia, Ethiopia.ORCID 0000-0002-1114-4849
Yohannes TekalegnDepartment of Public Health, School of Health Sciences, Madda Walabu University, Robe, Oromia, Ethiopia.
Demelash WoldeyohannesSchool of Public Health, College Medicine and Health Sciences, Wachemo University, Hossana, Ethiopia.
Daniel AtlawBiomedical Unit, School of Medicine, Madda Walabu University, Robe, Oromia, Ethiopia.
Fikadu NugusuDepartment of Public Health, School of Health Sciences, Madda Walabu University, Robe, Oromia, Ethiopia.
Lemlem Daniel BaffaDepartment of Human Nutrition, University of Gondar, Gondar, Ethiopia.
Degefa GomoraDepartment of Midwifery, School of Health Sciences, Madda Walabu University, Robe, Oromia, Ethiopia.
Girma BeressaDepartment of Public Health, School of Health Sciences, Madda Walabu University, Robe, Oromia, Ethiopia.ORCID 0000-0001-5677-3692

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDepression is one of the most common psychiatric disorders, affecting approximately 60% of people infected with the human immunodeficiency virus (HIV). Low and middle-income countries (LMICs), including Ethiopia, bear a disproportionate burden of depression among HIV/AIDS patients. Several factors, including perceived stigma, have been linked to increased depression among HIV/AIDS patients. Therefore, we aimed to estimate the pooled effect of perceived stigma on depression among HIV/AIDS patients in Ethiopia.

methodsFor this systematic review and meta-analysis, we systematically retrieved all relevant studies starting from January 1, 2000 to June 1, 2022 from PubMed, HINARI, and Google Scholar. This review included observational studies that reported the effect of perceived stigma on the prevalence of depression among HIV-positive adults in Ethiopia. The effect estimate of the pooled effect of perceived stigma on depression was conducted using DerSimonian-Laird's random effect model using STATA/MP version 16. An adjusted odds ratio (AOR), along with a 95% confidence interval (CI), was conducted to estimate the strength of the association between perceived stigma and depression.

resultsEleven studies with a total of 4,153 HIV-positive adults were included for meta-analysis. The results of the meta-analysis revealed that the odds of depression were higher among patients with perceived stigma (AOR: 3.78, 95% CI: 2.73, 5.24). The pooled prevalence of depression among HIV/AIDS patients in Ethiopia was 39% (95% CI: 32%, 46%) (I2 = 98%, p ≤ 0.0001). The subgroup analysis revealed that the primary studies conducted in the Oromia region had the highest pooled prevalence of depression at 48% (95% CI: 32%, 63%).

conclusionThe pooled estimates of the meta-analysis revealed that perceived stigma and depression were strongly associated. Stigma and depression screenings should be carried out for additional treatments and prevention, and programs supporting Ethiopia's PLWHA population should be strengthened.

Indexed as

DepressionHIV InfectionsSocial StigmaAdultEthiopiaFemaleHumansMalePrevalence

Identifiers

PMID38829859
PMCPMC11146698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.