Evidence map›Paper›PMID 38829802›Full record

ArticleJournal of the Pediatric Infectious Diseases Society2024

Immunogenicity, Immunological Memory and Monitoring of Disease Activity Following an Anamnestic Immunization With the 13-Valent Pneumococcal Conjugate Vaccine in Children With Idiopathic Nephrotic Syndrome.

Konstantina Kitsou, Varvara Askiti, Marianna Tzanoudaki, Andromachi Mitsioni, Ioanna Papadatou, Emmanouil Liatsis, Christina Kanaka-Gantenbein, Gkikas Magiorkinis, Vana Spoulou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Pediatric Infectious Diseases Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Konstantina KitsouImmunobiology and Vaccinology Research Laboratory, First Department of Pediatrics, "Aghia Sophia" Children's Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Varvara AskitiDepartment of Nephrology, "P. and A. Kyriakou" Children's Hospital, Athens, Greece.
Marianna TzanoudakiDepartment of Immunology and Histocompatibility, Specific Reference Centre for Primary Immunodeficiencies-Paediatric Immunology, "Aghia Sophia" Children's Hospital, Athens, Greece.
Andromachi MitsioniDepartment of Nephrology, "P. and A. Kyriakou" Children's Hospital, Athens, Greece.
Ioanna PapadatouImmunobiology and Vaccinology Research Laboratory, First Department of Pediatrics, "Aghia Sophia" Children's Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Emmanouil LiatsisDepartment of Immunology and Histocompatibility, Specific Reference Centre for Primary Immunodeficiencies-Paediatric Immunology, "Aghia Sophia" Children's Hospital, Athens, Greece.
Christina Kanaka-GantenbeinDivision of Endocrinology, Diabetes and Metabolism, First Department of Pediatrics, Medical School, Aghia Sophia Children's Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Gkikas MagiorkinisDepartment of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0002-0141-4753
Vana SpoulouImmunobiology and Vaccinology Research Laboratory, First Department of Pediatrics, "Aghia Sophia" Children's Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

Funding

European Society for Paediatric Infectious Diseases
6 · The paper itself

Abstract

Anamnestic 13-valent pneumococcal conjugate vaccine immunization did not affect the relapse risk in pediatric idiopathic nephrotic syndrome. Pneumococcal serotype (PS)-specific antibody titers increased significantly in all groups. Children receiving immunomodulatory treatments (IMTs) displayed significantly lower levels of PS-specific antibodies for 3/8 serotypes tested. PS-specific B-cell counts significantly increased only in healthy controls and patients receiving corticosteroids.

Indexed as

Antibodies, BacterialImmunologic MemoryNephrotic SyndromePneumococcal InfectionsPneumococcal VaccinesAdolescentB-LymphocytesChildChild, PreschoolFemaleHumansImmunogenicity, VaccineMaleStreptococcus pneumoniae13-valent pneumococcal vaccineAntibodies, BacterialPneumococcal Vaccinesidiopathic nephrotic syndromeimmunogenicityimmunological memorypneumococcal conjugate vaccinesafety

Identifiers

PMID38829802
PMCPMC11260040

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.