ArticleBJS open2024
Health-related quality of life by type of breast surgery in women with primary breast cancer: prospective longitudinal cohort study.
Article in BJS open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04227613 (Prospective Study of Cosmetic Outcome and Quality of Life for Women Undergoing Breast Cancer Surgery), which is not on this map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective Study of Cosmetic Outcome and Quality of Life for Women Undergoing Breast Cancer Surgery
Who cites it
4 citing papers in PubMed.
- Quality of Life After Breast Cancer Surgery in Patients Receiving Adjuvant Radiotherapy: A Cross-Sectional Analysis.European journal of breast health · 2026Article
- Quality of life in breast cancer survivors: a comparative analysis between breast conservative treatment (BCT) and post-mastectomy breast reconstruction (PMBR) using either autologous or prosthetic reconstruction.Updates in surgery · 2026Article
- Aesthetic Outcomes and Patient-Reported Outcomes of Volume Replacement (Chest Wall Perforator Flaps) versus Volume Displacement: An Observational Study.Aesthetic plastic surgery · 2026Observational
- The 19th St. Gallen international breast cancer conference 'primary therapy of patients with early breast cancer. Evidence, controversies, consensus': key moments and breakthroughs.Ecancermedicalscience · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundHealth-related quality of life and patient-related outcome measures for patients with cancer have gained increased interest over the last decade. However, few prospective studies with longitudinal data evaluated health-related quality of life in patients with breast cancer. This study aimed to investigate how health-related quality of life changed from the time of diagnosis to 1 year after breast cancer surgery for the main surgical techniques.
methodsThis prospective longitudinal single-centre study included patients with primary breast cancer diagnosed in 2019-2020 who underwent surgery. Patients completed a health-related quality of life questionnaire (Breast-Q) at baseline. One year after surgery, they completed the Breast-Q a second time, the EORTC (European Organization for Research and Treatment of Cancer) quality of life questionnaire-C30 and the quality of life questionnaire-BR23. Analysis of variance and Kruskal-Wallis tests were used to evaluate the differences in health-related quality of life between surgical groups. Analysis of covariance with robust standard errors was used to adjust for confounders.
resultsIn total, 340 patients were included in the study; 160 patients received oncoplastic partial mastectomy, 112 received partial mastectomy, 42 received mastectomy and 26 had mastectomy with immediate reconstruction. Patients that had partial mastectomy or oncoplastic partial mastectomy were more satisfied with their breasts (P < 0.001), had a better body image (P = 0.006) and higher sexual functioning scores (P = 0.027) than patients who had a mastectomy with/without reconstruction. The oncoplastic and mastectomy with reconstruction groups had more breast symptoms than other groups (P < 0.001), and the mastectomy group had the least symptoms from the chest area.
conclusionPartial mastectomy and oncoplastic partial mastectomy have the best outcomes in terms of breast satisfaction, body image and sexual functioning. This highlights the importance of preserving the breast when feasible and underscores that breast reconstruction is not equal to breast conservation. Registration number: NCT04227613 (http://www.clinicaltrials.gov).
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