Evidence map›Paper›PMID 38829690›Full record

ReviewJournal of medicinal chemistry2024

VHH Nanobody Versatility against Pentameric Ligand-Gated Ion Channels.

Dorota Nemecz, Weronika A Nowak, Ákos Nemecz

Erratum issuedAbstract readReview
In one paragraph

Review in Journal of medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Dorota NemeczBiochemistry Department, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.
Weronika A NowakBiochemistry Department, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.
Ákos NemeczBiochemistry Department, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.ORCID 0000-0002-1310-8964

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pentameric ligand-gated ion channels provide rapid chemical-electrical signal transmission between cells in the central and peripheral nervous system. Their dysfunction is associated with many nervous system disorders. They are composed of five identical (homomeric receptors) or homologous (heteromeric receptors) subunits. VHH nanobodies, or single-chain antibodies, are the variable domain, VH

Indexed as

Single-Domain AntibodiesAnimalsHumansLigand-Gated Ion ChannelsModels, MolecularLigand-Gated Ion ChannelsSingle-Domain Antibodies

Identifiers

PMID38829690
PMCPMC11181324

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.