Evidence map›Paper›PMID 38829526›Full record

SynthesisLangenbeck's archives of surgery2024

Transvaginal versus transabdominal specimen extraction in minimally invasive surgery: a systematic review and meta-analysis.

Jasmine Hui Er Chang, Hongyun Xu, Yun Zhao, Ian Jun Yan Wee, Joella Xiaohong Ang, Emile Kwong-Wei Tan, Isaac Seow-En

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in Langenbeck's archives of surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Review
  6. Comparison of transvaginal or transumbilical tissue extraction at laparoscopic gynecologic surgery: A 12-year experience.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jasmine Hui Er ChangDepartment of Colorectal Surgery, Singapore General Hospital, Outram Road, 169608, Singapore.
Hongyun XuDepartment of Colorectal Surgery, Singapore General Hospital, Outram Road, 169608, Singapore.
Yun ZhaoGroup Finance Analytics, Singapore Health Services, Singapore, Singapore.
Ian Jun Yan WeeDepartment of Colorectal Surgery, Singapore General Hospital, Outram Road, 169608, Singapore.
Joella Xiaohong AngDepartment of Obstetrics & Gynaecology, Singapore General Hospital, Outram Road, 169608, Singapore.
Emile Kwong-Wei TanDepartment of Colorectal Surgery, Singapore General Hospital, Outram Road, 169608, Singapore.
Isaac Seow-EnDepartment of Colorectal Surgery, Singapore General Hospital, Outram Road, 169608, Singapore. isaac.seow.en@gmail.com.ORCID https://orcid.org/0000-0001-8287-6812

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimNatural orifice specimen extraction (NOSE) is an alternative to conventional transabdominal retrieval. We aimed to compare outcomes following transvaginal specimen extraction (TVSE) and transabdominal specimen extraction (TASE) in minimally invasive abdominal surgery.

methodsAn electronic database search of PubMed, Embase and CENTRAL was performed from inception until March 2023. Comparative studies evaluating TVSE versus TASE in adult female patients were included. Studies involving transanal NOSE, endoluminal surgery, or TVSE with concomitant hysterectomy were excluded. Weighted mean differences (WMD) and odds ratio were estimated for continuous and dichotomous outcomes respectively. Primary outcomes were postoperative day 1 (POD1) pain and length of stay (LOS). Secondary outcomes were operative time, rescue analgesia, morbidity, and cosmesis. A review of sexual, oncological, and technical outcomes was performed.

resultsThirteen studies (2 randomised trials, 11 retrospective cohort studies), involving 1094 patients (TASE 583, TVSE 511), were included in the analysis. Seven studies involved colorectal disease and six assessed gynaecological conditions. TVSE resulted in significantly decreased POD1 pain (WMD 1.08, 95% CI: 0.49, 1.68) and shorter LOS (WMD 1.18 days, 95% CI: 0.14, 2.22), compared to TASE. Operative time was similar between both groups, with fewer patients requiring postoperative rescue analgesia with TVSE. Overall morbidity rates, as well as both wound-related and non-wound related complication rates were better with TVSE, while anastomotic morbidity rates were comparable. Cosmetic scores were higher with TVSE. TVSE did not result in worse sexual or oncological outcomes.

conclusionTVSE may be feasible and beneficial compared to TASE when performed by proficient laparoscopic operators, using appropriate selection criteria. Continued evaluation with prospective studies is warranted.

Indexed as

Minimally Invasive Surgical ProceduresVaginaFemaleHumansLength of StayNatural Orifice Endoscopic SurgeryOperative TimeLaparoscopic surgeryMeta-analysisNatural orifice specimen extractionTransvaginal

Identifiers

PMID38829526
PMCPMC11147895

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.