ArticleJournal of epidemiology and global health2024
Incidence and Outcomes of Brucella Endocarditis in a High-Prevalence Area: A Single-Center Study.
Article in Journal of epidemiology and global health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Molecular frequency ofNew microbes and new infections · 2026Article
- Successful Conservative Management of ComplicatedJournal of medical cases · 2026Article
- Development and validation of a clinico-biological score for Brucella spondylitis: a two-center study.BMC infectious diseases · 2025Article
- A case of hepatic-splenic abscess in a non-endemic area of brucellosis: insights from complex infection with brucellosis.BMC infectious diseases · 2025Article
- Comparative analysis of clinical features of brucellosis in Kashi and Guangzhou: a retrospective multicentre study.BMC infectious diseases · 2025Article
- Clinical Insights into Brucella Peritonitis: A Comprehensive Analysis of Four Cases.Journal of epidemiology and global health · 2024Article
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Authors and funding
9 authors.
Funding
Abstract
objectiveTo analyze the clinical characteristics of Brucella endocarditis (BE) and observe the factors related to death to provide guidance for clinical treatment.
methodsThis study examined all patients with BE admitted to The First People's Hospital of Kashi Prefecture between January 2017 and November 2023. Clinical characteristics and follow-up outcomes were collected for analysis.
resultsThis study revealed 774 cases of brucellosis and 14 cases of BE, with an overall incidence rate of 1.88%. Most of the patients were male (71.43%) and lived in areas where brucellosis is common. Patients ranged in age from 26 to 68 years. Common symptoms reported among patients included chest tightness and fatigue, and a significant portion also presented with congestive heart failure. Most patients exhibited normal white blood cell counts (WBC) but had elevated levels of C-reactive protein (CRP). Transthoracic ultrasound (TTE) revealed cardiac valve vegetation in all patients, along with positive blood cultures. Six patients (42.86%) completed heart surgery, and ten (71.43%) completed anti-infection treatment. Six patients died, five of whom did not undergo surgery. The other patient with Marfan syndrome died after surgery. Sex, WBC count, neutrophil (NEUT) and total bilirubin (TBIL) were significant factors associated with regression in BE patients (P < 0.05) according to univariate analysis.
conclusionsPatients with BE in Kashi have a severe clinical presentation at diagnosis, but early detection with improved cardiac ultrasound and aggressive treatment can improve the prognosis.
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