Evidence map›Paper›PMID 38829283›Full record

ArticleEnvironmental science & technology2024

Analysis of Legacy and Novel Neutral Per- and Polyfluoroalkyl Substances in Soils from an Industrial Manufacturing Facility.

W Matthew Henderson, Marina G Evich, John W Washington, Thomas T Ward, Brian A Schumacher, John H Zimmerman, Yung D Kim, Eric J Weber, Alan C Williams, Marci G Smeltz and 1 more

Abstract read
In one paragraph

Article in Environmental science & technology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

W Matthew HendersonU.S. Environmental Protection Agency, ORD/CEMM/EPD, Athens, Georgia 30605, United States.ORCID 0000-0002-2800-8536
Marina G EvichU.S. Environmental Protection Agency, ORD/CEMM/EPD, Athens, Georgia 30605, United States.ORCID 0000-0002-2386-0682
John W WashingtonU.S. Environmental Protection Agency, ORD/CEMM/EPD, Athens, Georgia 30605, United States.
Thomas T WardOak Ridge Institute for Science and Education, ORD/CEMM/EPD, Athens, Georgia 30605, United States.
Brian A SchumacherU.S. Environmental Protection Agency, ORD/CEMM/EPD, Athens, Georgia 30605, United States.ORCID 0000-0001-8202-2630
John H ZimmermanU.S. Environmental Protection Agency, ORD/CEMM/WECD, Research Triangle Park, North Carolina 27711, United States.ORCID 0000-0002-0909-0079
Yung D KimOak Ridge Institute for Science and Education, ORD/CEMM/EPD, Athens, Georgia 30605, United States.
Eric J WeberU.S. Environmental Protection Agency, ORD/CEMM/EPD, Athens, Georgia 30605, United States.
Alan C WilliamsU.S. Environmental Protection Agency, ORD/CEMM/WECD, Research Triangle Park, North Carolina 27711, United States.
Marci G SmeltzU.S. Environmental Protection Agency, ORD/CPHEA/PHITD, Research Triangle Park, North Carolina 27711, United States.
Donna A GlinskiU.S. Environmental Protection Agency, ORD/CEMM/EPD, Athens, Georgia 30605, United States.ORCID 0000-0001-7934-5666

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

Per- and polyfluoroalkyl substances (PFASs) have been detected in an array of environmental media due to their ubiquitous use in industrial and consumer products as well as potential release from fluorochemical manufacturing facilities. During their manufacture, many fluorotelomer (FT) facilities rely on neutral intermediates in polymer production including the FT-alcohols (FTOHs). These PFAS are known to transform to the terminal acids (perfluoro carboxylic acids; PFCAs) at rates that vary with environmental conditions. In the current study on soils from a FT facility, we employed gas chromatography coupled with conventional- and high-resolution mass spectrometry (GC-MS and GC-HRMS) to investigate the profile of these precursor compounds, the intermediary secondary alcohols (sFTOHs), FT-acrylates (FTAcr), and FT-acetates (FTAce) in soils around the former FT-production facility. Of these precursors, the general trend in detection intensity was [FTOHs] > [sFTOHs] > [FTAcrs], while for the FTOHs, homologue intensities generally were [12:2 FTOH] > [14:2 FTOH] > [16:2 FTOH] > [10:2 FTOH] > [18:2 FTOH] > [20:2 FTOH] > [8:2 FTOH] ∼ [6:2 FTOH]. The corresponding terminal acids were also detected in all soil samples and positively correlated with the precursor concentrations. GC-HRMS confirmed the presence of industrial manufacturing byproducts such as FT-ethers and FT-esters and aided in the tentative identification of previously unreported dimers and other compounds. The application of GC-HRMS to the measurement and identification of precursor PFAS is in its infancy, but the methodologies described here will help refine its use in tentatively identifying these compounds in the environment.

Indexed as

FluorocarbonsSoilSoil PollutantsEnvironmental MonitoringGas Chromatography-Mass SpectrometryManufacturing and Industrial FacilitiesFluorocarbonsSoilSoil Pollutantscontaminated soilsfluorotelomer alcoholsneutral PFASPFCA precursorsSemivolatile PFAS

Identifiers

PMID38829283
PMCPMC11304343

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.