ArticleeLife2024
Glutamatergic supramammillary nucleus neurons respond to threatening stressors and promote active coping.
Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
7 citing papers in PubMed.
- Hippocampal long-range GABAergic neurons target hippocampal-projecting cells of the supramammillary area.The Journal of physiology · 2026Article
- Article
- A Preoptic Neuronal Population Regulates Energy Expenditure and Balance.bioRxiv : the preprint server for biology · 2026Article
- Stress ensemble in the BNST mediates comorbid anxiety and sleep disruption.Science advances · 2026Article
- Prefrontal corticotropin-releasing factor promotes resilience to social stress.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Activation of the supramammillary-dentate gyrus circuit enhances alertness and cognitive function in a rat model of ADHD.Translational psychiatry · 2025Article
- Hypothalamic Supramammillary Control of Cognition and Motivation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Review
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Threat-response neural circuits are conserved across species and play roles in normal behavior and psychiatric diseases. Maladaptive changes in these neural circuits contribute to stress, mood, and anxiety disorders. Active coping in response to stressors is a psychosocial factor associated with resilience against stress-induced mood and anxiety disorders. The neural circuitry underlying active coping is poorly understood, but the functioning of these circuits could be key for overcoming anxiety and related disorders. The supramammillary nucleus (SuM) has been suggested to be engaged by threat. SuM has many projections and a poorly understood diversity of neural populations. In studies using mice, we identified a unique population of glutamatergic SuM neurons (SuM
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.