Evidence map›Paper›PMID 38829138›Full record

ArticleJournal of virology2024

A full-length glycoprotein mRNA vaccine confers complete protection against severe fever with thrombocytopenia syndrome virus, with broad-spectrum protective effects against bandaviruses.

Jia Lu, Jun Liu, Yan Wu, Xiaoxue He, Xiao Gao, Xinlan Chen, Shaoyi Chen, Xuerui Zhu, Yucai Peng, Gengfu Xiao and 1 more

Abstract read
In one paragraph

Article in Journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jia Lu *State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Jun Liu *Liverna Therapeutics Inc., Zhuhai, China.
Yan WuState Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Xiaoxue HeState Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Xiao GaoState Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Xinlan ChenState Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Shaoyi ChenLiverna Therapeutics Inc., Zhuhai, China.
Xuerui ZhuState Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Yucai PengLiverna Therapeutics Inc., Zhuhai, China.ORCID 0009-0001-4865-0956
Gengfu XiaoState Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.ORCID 0000-0001-9401-235X
Xiaoyan PanState Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.ORCID 0000-0003-0553-5138

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Highly pathogenic viruses from family IMPORTANCE: Tick-borne bandaviruses, such as SFTSV and Heartland virus, sporadically trigger outbreaks in addition to influenza viruses and coronaviruses, yet there are no specific vaccines or therapeutics against them. mRNA vaccine technology has advantages in terms of enabling

Indexed as

GlycoproteinsPhlebovirusSevere Fever with Thrombocytopenia SyndromeViral VaccinesAnimalsAntibodies, ViralCross ProtectionFemaleImmunity, CellularMiceMice, Inbred BALB CmRNA VaccinesVaccines, SyntheticAntibodies, ViralGlycoproteinsmRNA VaccinesVaccines, SyntheticViral Vaccinesbroad-spectrum protectioncellular immunologyconserved epitopeglycoproteinsevere fever with thrombocytopenia syndrome virus

Identifiers

PMID38829138
PMCPMC11265342

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.