Evidence map›Paper›PMID 38829048›Full record

ArticlemSystems2024

The hallmarks of a tradeoff in transcriptomes that balances stress and growth functions.

Christopher Dalldorf, Kevin Rychel, Richard Szubin, Ying Hefner, Arjun Patel, Daniel C Zielinski, Bernhard O Palsson

Abstract read
In one paragraph

Article in mSystems, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. The roles and synthesis of inorganic polyphosphate inbioRxiv : the preprint server for biology · 2026
    Article
  3. Review
  4. Article
  5. A systems-level atlas of carbon-response transcriptional states inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Christopher DalldorfDepartment of Bioengineering, University of California San Diego, La Jolla, USA.ORCID 0009-0004-9522-9648
Kevin RychelDepartment of Bioengineering, University of California San Diego, La Jolla, USA.
Richard SzubinDepartment of Bioengineering, University of California San Diego, La Jolla, USA.
Ying HefnerDepartment of Bioengineering, University of California San Diego, La Jolla, USA.
Arjun PatelDepartment of Bioengineering, University of California San Diego, La Jolla, USA.
Daniel C ZielinskiDepartment of Bioengineering, University of California San Diego, La Jolla, USA.
Bernhard O PalssonDepartment of Bioengineering, University of California San Diego, La Jolla, USA.ORCID 0000-0003-2357-6785

Funding

GENOMICALLY BASED MODELS FOR ANTIBIOTIC DEVELOPMENTR01GM057089 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PALSSON, BERNHARD O · 1998 to 2021
$6.9M
HHS | NIH | OSC | Common Fund (NIH Common Fund) GM057089NIGMS NIH HHS R01 GM057089Novo Nordisk Fonden (NNF) NNF20CC0035580Y.C. Fung Endowed Chair at UCSD
6 · The paper itself

Abstract

Fast growth phenotypes are achieved through optimal transcriptomic allocation, in which cells must balance tradeoffs in resource allocation between diverse functions. One such balance between stress readiness and unbridled growth in

Indexed as

DNA-Directed RNA PolymerasesEscherichia coliMutationStress, PhysiologicalTranscriptomeAdaptation, PhysiologicalEscherichia coli ProteinsGene Expression Regulation, BacterialSigma FactorDNA-Directed RNA PolymerasesEscherichia coli ProteinsSigma FactorEscherichia coliribosomessigma factorstranscriptional regulation

Identifiers

PMID38829048
PMCPMC11264592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.