Evidence map›Paper›PMID 38829032›Full record

ArticleJournal of addiction medicine

Provider Perceptions Toward Extended-Release Buprenorphine for Treatment of Opioid Use Disorder.

India A Reddy, Carolyn M Audet, Thomas J Reese, Grayson Peek, David Marcovitz

Abstract read
In one paragraph

Article in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Long-Acting injectable buprenorphine PLGA microparticle formulation.International journal of pharmaceutics · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

India A ReddyFrom the Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN (IAR, DM); Department of Health Policy, Vanderbilt University Medical Center, Nashville, TN (CMA); Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN (TJR); and Department of Pharmaceutical Services, Vanderbilt University Medical Center, Nashville, TN (GP).
Carolyn M Audet
Thomas J Reese
Grayson Peek
David Marcovitz

Funding

Optimal Methods for Estimating Policy Effect Heterogeneity in Opioid Policy ResearchP50DA046351 · NIDA · RAND CORPORATION · PI Rosanna Smart · 2018 to 2026
$20.8M
Vanderbilt Integrated Center of Excellence in Maternal and Pediatric Precision Therapeutics (VICE-MPRINT)P50HD106446 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PRINCE Joseph KANNANKERIL, Digna R Velez Edwards · 2021 to 2026
$9.7M
Patient-centered decision making to improve opioid use disorder treatmentK08HS029695 · AHRQ · VANDERBILT UNIVERSITY MEDICAL CENTER · PI REESE, THOMAS J · 2023 to 2024
$289k
AHRQ HHS K08 HS029695NICHD NIH HHS P50 HD106446NIDA NIH HHS P50 DA046351
6 · The paper itself

Abstract

objectivesThe persistence of the opioid crisis and the proliferation of synthetic fentanyl have heightened the demand for the implementation of novel delivery mechanisms of pharmacotherapy for the treatment of opioid use disorder, including injectable extended-release buprenorphine (buprenorphine-ER). The purpose of this study was to understand provider-level barriers to prescribing buprenorphine in order to facilitate targeted strategies to improve implementation for patients who would benefit from this novel formulation.

methodsUsing an interview template adapted from the Consolidated Framework for Implementation Research (CFIR), we conducted structured focus group interviews with 20 providers in an outpatient addiction clinic across 4 sessions to assess providers' perceptions of buprenorphine-ER. Ninety-four unique comments were identified and deductively coded using standardized CFIR constructs.

resultsProviders expressed mixed receptivity and confidence in using buprenorphine-ER. Although providers could identify a number of theoretical advantages to the injectable formulation over sublingual buprenorphine, many expressed reservations about using it due to inexperience, negative patient experiences, uncertainties about patient candidacy, cost, and logistical constraints.

conclusionsProvider concerns about buprenorphine-ER may limit utilization. Some concerns may be mitigated through improved education, research, and logistical support. Given the putative benefits of buprenorphine-ER, future research should target barriers to implementation, in part based on hypotheses generated by these findings.

Indexed as

Attitude of Health PersonnelBuprenorphineDelayed-Action PreparationsFocus GroupsOpiate Substitution TreatmentOpioid-Related DisordersAdultAnalgesics, OpioidFemaleHumansMaleMiddle AgedNarcotic AntagonistsAnalgesics, OpioidBuprenorphineDelayed-Action PreparationsNarcotic Antagonists

Identifiers

PMID38829032
PMCPMC11446660

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.