Evidence map›Paper›PMID 38828957›Full record

Trial reportJournal of clinical oncology : official journal of the American Society of Clinical Oncology2024

CNS Protective Effect of Selpercatinib in First-Line

Maurice Pérol, Benjamin J Solomon, Koichi Goto, Keunchil Park, Ernest Nadal, Emilio Bria, Claudio Martin, Jair Bar, Justin N Williams, Tarun Puri and 4 more

Abstract readRandomized Controlled TrialClinical Trial, Phase IIIMulticenter Study
In one paragraph

Trial report in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Selpercatinib inJournal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025
    Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
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  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Maurice PérolCentre Léon Bérard, Lyon, France.ORCID 0000-0002-3296-423X
Benjamin J SolomonPeter MacCallum Cancer Institute, Melbourne, VIC, Australia.ORCID 0000-0003-3059-5730
Koichi GotoNational Cancer Center Hospital East, Kashiwa, Japan.ORCID 0000-0002-3023-2510
Keunchil ParkSamsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.ORCID 0000-0002-4846-7449
Ernest NadalInstitut Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain.ORCID 0000-0002-9674-5554
Emilio BriaFondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy.ORCID 0000-0002-2333-704X
Claudio MartinInstituto Alexander Fleming, Buenos Aires, Argentina.ORCID 0000-0003-4135-7332
Jair BarInstitute of Oncology, Sheba Medical Center, Ramat Gan, Israel.ORCID 0000-0002-1224-3646
Justin N WilliamsEli Lilly and Company, Indianapolis, IN.ORCID 0000-0003-2341-2596
Tarun PuriEli Lilly and Company, Indianapolis, IN.ORCID 0000-0003-2399-4362
Jian LiEli Lilly and Company, Indianapolis, IN.
Minji K UhEli Lilly and Company, Indianapolis, IN.
Boris K LinEli Lilly and Company, Indianapolis, IN.
Caicun ZhouShanghai Pulmonary Hospital, Shanghai, China.ORCID 0000-0002-1072-9941

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsProto-Oncogene Proteins c-retPyrazolesPyridinesAdultAgedAntibodies, Monoclonal, HumanizedAntineoplastic Combined Chemotherapy ProtocolsBrain NeoplasmsCentral Nervous System NeoplasmsFemaleHumansMaleMiddle AgedOncogene Proteins, FusionAntibodies, Monoclonal, HumanizedOncogene Proteins, FusionpembrolizumabPemetrexedProto-Oncogene Proteins c-retPyrazolesPyridinesRET protein, humanselpercatinib

Identifiers

PMID38828957
PMCPMC11268557

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.