Evidence map›Paper›PMID 38828914›Full record

ReviewDrug delivery2024

Advances in cell membrane-based biomimetic nanodelivery systems for natural products.

Yifeng Zhang, Qian Zhang, Chunhong Li, Ziyun Zhou, Hui Lei, Minghua Liu, Dan Zhang

Abstract readReview
In one paragraph

Review in Drug delivery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yifeng ZhangSchool of Pharmacy, Southwest Medical University, Luzhou, P. R. China.
Qian ZhangSchool of Pharmacy, Southwest Medical University, Luzhou, P. R. China.
Chunhong LiSchool of Pharmacy, Southwest Medical University, Luzhou, P. R. China.
Ziyun ZhouSchool of Pharmacy, Southwest Medical University, Luzhou, P. R. China.
Hui LeiSchool of Pharmacy, Southwest Medical University, Luzhou, P. R. China.
Minghua LiuSchool of Pharmacy, Southwest Medical University, Luzhou, P. R. China.
Dan ZhangSchool of Pharmacy, Southwest Medical University, Luzhou, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Active components of natural products, which include paclitaxel, curcumin, gambogic acid, resveratrol, triptolide and celastrol, have promising anti-inflammatory, antitumor, anti-oxidant, and other pharmacological activities. However, their clinical application is limited due to low solubility, instability, low bioavailability, rapid metabolism, short half-life, and strong off-target toxicity. To overcome these drawbacks, cell membrane-based biomimetic nanosystems have emerged that avoid clearance by the immune system, enhance targeting, and prolong drug circulation, while also improving drug solubility and bioavailability, enhancing drug efficacy, and reducing side effects. This review summarizes recent advances in the preparation and coating of cell membrane-coated biomimetic nanosystems and in their applications to disease for targeted natural products delivery. Current challenges, limitations, and prospects in this field are also discussed, providing a research basis for the development of multifunctional biomimetic nanosystems for natural products.

Indexed as

Biological ProductsCell MembraneAnimalsBiological AvailabilityBiomimetic MaterialsBiomimeticsDrug Delivery SystemsHumansNanoparticlesSolubilityBiological Productsactive componentsbiomimeticcell membrane-basednanosystemsnatural products

Identifiers

PMID38828914
PMCPMC11149581

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.