Evidence map›Paper›PMID 38828622›Full record

ArticleAmerican journal of Alzheimer's disease and other dementias

Mediating Factors Associated With Physical Activity in Older Adults at Increased Dementia Risk.

Maria Isabel Cardona, Melanie Luppa, Andrea Zülke, Eric S Kroeber, Alexander Bauer, Juliane Döhring, Catharina Escales, Christian Brettschneider, Thomas Frese, Robert P Kosilek and 7 more

Abstract read
In one paragraph

Article in American journal of Alzheimer's disease and other dementias. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Maria Isabel CardonaGerman Center for Neurodegenerative Diseases (DZNE), Site Rostock/Greifswald, Greifswald, Germany.ORCID 0000-0003-2614-4670
Melanie LuppaInstitute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, Leipzig, Germany.
Andrea ZülkeInstitute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, Leipzig, Germany.
Eric S KroeberInstitute of General Practice and Family Medicine, Martin-Luther-University Halle-Wittenberg, Halle, Germany.
Alexander BauerInstitute of General Practice and Family Medicine, Martin-Luther-University Halle-Wittenberg, Halle, Germany.
Juliane DöhringInstitute of General Practice, University of Kiel, Kiel, Germany.
Catharina EscalesInstitute of General Practice, University of Kiel, Kiel, Germany.
Christian BrettschneiderDepartment of Health Economics and Health Service Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0002-5280-1075
Thomas FreseInstitute of General Practice and Family Medicine, Martin-Luther-University Halle-Wittenberg, Halle, Germany.
Robert P KosilekInstitute of General Practice and Family Medicine, University Hospital, LMU Munich, Munich, Germany.
Jochen GensichenInstitute of General Practice and Family Medicine, University Hospital, LMU Munich, Munich, Germany.
Wolfgang HoffmannGerman Center for Neurodegenerative Diseases (DZNE), Site Rostock/Greifswald, Greifswald, Germany.ORCID 0000-0002-6359-8797
Hanna KaduszkiewiczInstitute of General Practice, University of Kiel, Kiel, Germany.
Hans-Helmut KönigDepartment of Health Economics and Health Service Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Birgitt WieseMHH Information Technology, Hannover Medical School, Hannover, Germany.
Steffi G Riedel-HellerInstitute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, Leipzig, Germany.
Jochen René ThyrianGerman Center for Neurodegenerative Diseases (DZNE), Site Rostock/Greifswald, Greifswald, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While regular physical-activity (PA) is beneficial, multimorbid individuals at increased dementia risk may exhibit reduced PA levels. Thus, a more comprehensive understanding of mediating factors responsible for inactivity in this population is needed. This study investigated the impact of a multimodal intervention on PA changes at 24-month follow-up and associated mediating factors among community-dwelling patients aged 60-77, with increased dementia risk determined by the CAIDE Dementia Risk Score. Of 1030 participants recruited, 819 completed the assessment. Thus, a generalized estimating equations model initially assessed differences in PA over 24 months, followed by a tree analysis identifying mediating factors influencing PA changes post-intervention. While no significant effect on regular PA was found during the follow-up (

Indexed as

DementiaExerciseSelf EfficacyAgedFemaleFollow-Up StudiesHumansIndependent LivingMaleMiddle AgedMultimorbidityRisk Factorsdecision tree analysisdementiamediating factorsmultimorbidityphysical activity

Identifiers

PMID38828622
PMCPMC11149443

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.